Development of three-dimensional haptotaxis model for single crawling cell

被引:0
作者
Jihwan Song
Dongchoul Kim
机构
[1] Sogang University,Department of Mechanical Engineering
来源
BioChip Journal | 2010年 / 4卷
关键词
Haptotaxis; Sing crawling cell; Cell migration; Morphology; Interface energy; Diffuse interface model;
D O I
暂无
中图分类号
学科分类号
摘要
This paper proposes a three-dimensional diffuse interface dynamic model with multiple mechanisms and confirms the high possibility of adequate predictions. In particular, we consider the nucleus that exhibits three-dimensional motion in the crawling cell, which enables a more realistic representation of haptotactic migration. A diffuse interface model that incorporates the haptotaxis mechanism and interface energies is employed. The semi-implicit Fourier spectral scheme is adopted for efficient evaluation of the simulation model. The simulation results confirm the reliability of the developed model.
引用
收藏
页码:184 / 188
页数:4
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