Rotation of the γ Subunit in F1-ATPase; Evidence That ATP Synthase Is a Rotary Motor Enzyme

被引:0
作者
Ryohei Yasuda
Hiroyuki Noji
Kazuhiko Kinosita
Fumihiro Motojima
Masasuke Yoshida
机构
[1] Keio University,Department of Physics, Faculty of Science and Technology
[2] Tokyo Institute of Technology,Research Laboratory of Resources Utilization
来源
Journal of Bioenergetics and Biomembranes | 1997年 / 29卷
关键词
ATP synthase; F; -ATPase; rotary motor; single molecule imaging; loose coupling;
D O I
暂无
中图分类号
学科分类号
摘要
ATP-dependent, azide-sensitive rotation of the γ subunit relative to the α3β3 hexagonal ring of ATP synthase was observed with a single molecule imaging system. Thus, ATP synthase is a rotary motor enzyme, the first ever found.
引用
收藏
页码:207 / 209
页数:2
相关论文
共 50 条
  • [31] A model of stepping kinetics for rotary enzymes. Application to the F1-ATPase
    Goldstein, B. N.
    Aksirov, A. M.
    Zakrjevskaya, D. T.
    BIOSYSTEMS, 2011, 104 (01) : 9 - 13
  • [32] Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
    Mukherjee, Shayantani
    Warshel, Arieh
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (51) : 20550 - 20555
  • [33] The γ-subunit rotation and torque generation in F1-ATPase from wild-type or uncoupled mutant Escherichia coli
    Omote, H
    Sambonmatsu, N
    Saito, K
    Sambongi, Y
    Iwamoto-Kihara, A
    Yanagida, T
    Wada, Y
    Futai, M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (14) : 7780 - 7784
  • [34] The nonlinear chemo-mechanic coupled dynamics of the F1-ATPase molecular motor
    Lizhong Xu
    Fang Liu
    Journal of Biological Physics, 2012, 38 : 209 - 227
  • [35] The ζ subunit of the F1FO-ATP synthase of α-proteobacteria controls rotation of the nanomotor with a different structure
    Zarco-Zavala, Mariel
    Morales-Rios, Edgar
    Mendoza-Hernandez, Guillermo
    Ramirez-Silva, Leticia
    Perez-Hernandez, Gerardo
    Garcia-Trejo, Jose J.
    FASEB JOURNAL, 2014, 28 (05) : 2146 - 2157
  • [36] Why Is the Mechanical Efficiency of F1-ATPase So High?
    George Oster
    Hongyun Wang
    Journal of Bioenergetics and Biomembranes, 2000, 32 : 459 - 469
  • [37] Angle-dependent rotation velocity consistent with ADP release in bacterial F1-ATPase
    Suiter, Nathan
    Volkan-Kacso, Sandor
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 10
  • [38] Kinetic analysis of rotary F0F1-ATP synthase
    Rumberg, B
    Pänke, O
    PHOTOSYNTHESIS: MECHANISMS AND EFFECTS, VOLS I-V, 1998, : 1643 - 1648
  • [39] Twisting and subunit rotation in single FOF1-ATP synthase
    Sielaff, Hendrik
    Boersch, Michael
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2013, 368 (1611)
  • [40] F1-ATPase Rotary Mechanism: Interpreting Results of Diverse Experimental Modes With an Elastic Coupling Theory
    Volkan-Kacso, Sandor
    Marcus, Rudolph A.
    FRONTIERS IN MICROBIOLOGY, 2022, 13