Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer

被引:0
作者
Michael Z Gilcrease
Xiao Zhou
Xiaolin Lu
Wendy A Woodward
Brian E Hall
Phillip J Morrissey
机构
[1] The University of Texas M.D. Anderson Cancer Center,Department of Pathology
[2] The University of Texas M.D. Anderson Cancer Center,Department of Radiation Oncology
[3] Amnis Corporation,undefined
来源
Journal of Experimental & Clinical Cancer Research | / 28卷
关键词
Breast Carcinoma Cell Line; EGFR Signaling; Growth Factor Receptor Signaling; Basal Subtype; Integrin Cluster;
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[1]  
Hynes RO(2002)Integrins: bidirectional, allosteric signaling machines Cell 110 673-687
[2]  
Miranti CK(2002)Sensing the environment: a historical perspective on integrin signal transduction Nat Cell Biol 4 E83-90
[3]  
Brugge JS(1998)Integrin affinity modulation Trends Cell Biol 8 359-364
[4]  
Hughes PE(2003)Cell migration: integrating signals from front to back Science 302 1704-1709
[5]  
Pfaff M(1995)Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function Science 267 883-885
[6]  
Ridley AJ(1998)LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain J Cell Biol 140 699-707
[7]  
Schwartz MA(1999)The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes J Biol Chem 274 26869-26877
[8]  
Burridge K(2002)Networks and crosstalk: integrin signalling spreads Nat Cell Biol 4 E65-68
[9]  
Firtel RA(1996)Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors J Cell Biol 135 1633-1642
[10]  
Ginsberg MH(1999)Integrin function in breast carcinoma progression J Mammary Gland Biol Neoplasia 4 367-376