Akt2 relaxes podocytes in chronic kidney disease

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作者：

Jochen Reiser

机构：

[1] Rush University,Jochen Reiser is at the Department of Medicine

[2] Chicago,undefined

[3] Illinois,undefined

[4] USA.,undefined

来源：

Nature Medicine | 2013年 / 19卷

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摘要：

A signaling cascade is activated in podocytes to induce survival and cope with stress during advanced glomerular disease, a new study shows. The findings may also explain why the immunosuppressor sirolimus, an inhibitor of this pathway, can cause proteinuria in a subset of patients with chronic kidney disease (pages 1288–1296).

引用

页码：1212 / 1213

页数：1