Illuminating cortactin structure and function at actin filament branches

被引：0

作者：

Rottner, Klemens ^{[1
,2
]}

Bieling, Peter ^{[3
]}

机构：

[1] Helmholtz Ctr Infect Res, Dept Cell Biol, Braunschweig, Germany

[2] Tech Univ Carolo Wilhelmina Braunschweig, Zool Inst, Div Mol Cell Biol, Braunschweig, Germany

[3] Max Planck Inst Mol Physiol, Dept Syst Cell Biol, Dortmund, Germany

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2024年 / 31卷 / 05期

关键词：

D O I：

10.1038/s41594-024-01297-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Stabilization of a branch structure would intuitively suggest a direct connection between trunk and bough, but in actin filament networks, cortactin clamps the branching Arp2/3 complex to the daughter filament. This has fundamental consequences for mechanistic understanding of actin branch turnover and cortactin biology.

引用

页码：739 / 741

页数：3

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