Diterpenoids from the Roots of Salvia yunnanensis

被引:13
作者
Xia F. [1 ]
Wu C.-Y. [2 ]
Yang X.-W. [2 ]
Li X. [1 ]
Xu G. [2 ]
机构
[1] School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming
[2] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming
基金
中国国家自然科学基金;
关键词
Cytotoxicity; Diterpenoid; Salvia yunnanensis;
D O I
10.1007/s13659-015-0080-4
中图分类号
学科分类号
摘要
Abstract: Two new diterpenoids, salyunnanins I and J (1 and 2), together with ten analogues, were isolated from the roots of Salvia yunnanensis. The structures of the new isolates, possessing different neo-clerodane and seco-abietane diterpenoid skeletons respectively, were elucidated on the basis of comprehensive spectroscopic data. All of the compounds were tested for the inhibitory activities against six human tumor lines in vitro, and several ones showed moderate cytotoxic activities. Graphical Abstract: [Figure not available: see fulltext.] © 2015, The Author(s).
引用
收藏
页码:307 / 312
页数:5
相关论文
共 50 条
  • [11] Abietane Diterpenoids and a Lignan from Pinus yunnanensis
    Feng, Tao
    Cai, Xiang-Hai
    Tan, Qin-Gang
    Luo, Xiao-Dong
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2010, 65 (06): : 765 - 769
  • [12] Qualitative analysis of the roots of Salvia miltiorrhiza and Salvia yunnanensis based on NIR, UHPLC and LC-MS-MS
    Ni, Lijun
    Zhang, Fangfang
    Han, Mingyue
    Zhang, Liguo
    Luan, Shaorong
    Li, Wei
    Deng, Haixing
    Lan, Zhuhui
    Wu, Zhongxiang
    Luo, Xiaofang
    Mleczko, Leslaw
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 170 : 295 - 304
  • [13] Cytotoxic diterpenoids from the roots of Euphorbia stracheyi
    Ye, Ye
    Liu, Guang-Hui
    Dawa, Drolma
    Ding, Li-Sheng
    Cao, Zhi-Xing
    Zhou, Yan
    PHYTOCHEMISTRY LETTERS, 2020, 36 : 183 - 187
  • [14] Plebeins A-F, sesquiterpenoids and diterpenoids from Salvia plebeian
    Zhang, Cheng-Gang
    Jin, Min-Rong
    Chou, Gui-Xin
    Yang, Qing-Shan
    PHYTOCHEMISTRY LETTERS, 2017, 19 : 254 - 258
  • [15] Cytotoxic Diterpenoids from the Roots of Aralia melanocarpa
    Jiang, Zhi-Yong
    Yang, Chun-Tao
    Hou, Shu-Qun
    Tian, Kai
    Wang, Wei
    Hu, Qiu-Fen
    Huang, Xiang-Zhong
    PLANTA MEDICA, 2016, 82 (08) : 742 - 746
  • [16] Cytotoxic activity of abietane diterpenoids from roots of Salvia sahendica by HPLC-based activity profiling
    Moradi-Afrapoli, Fahimeh
    Shokrzadeh, Mohammad
    Barzegar, Fatemeh
    Gorji-Bahri, Gilar
    Zadali, Reza
    Ebrahimi, Samad Nejad
    REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2018, 28 (01): : 27 - 33
  • [17] Bioactive labdane diterpenoids from Salvia leriifolia
    Ebrahimi, S. N.
    Farimani, M. M.
    Taleghani, A.
    Aliabadi, A.
    Aliahmadi, A.
    Esmaeili, M. A.
    Sarvestani, N. N.
    Khavasi, H. R.
    Smiesko, M.
    Hamburger, M.
    PLANTA MEDICA, 2016, 82
  • [18] Bioactive diterpenoids isolated from Salvia mellifera
    Moujir, L
    GutierrezNavarro, AM
    Andres, LS
    Luis, JG
    PHYTOTHERAPY RESEARCH, 1996, 10 (02) : 172 - 174
  • [19] Two New Diterpenoids from Salvia przewarskii
    Tsukada, Haruka
    Kawabe, Hiroshi
    Ohtaka, Aya
    Saito, Yoshinori
    Okamoto, Yasuko
    Tori, Motoo
    Kagechika, Hiroyuki
    Hirota, Hiroshi
    Gong, Xun
    Kuroda, Chiaki
    Ohsaki, Ayumi
    NATURAL PRODUCT COMMUNICATIONS, 2016, 11 (02) : 159 - 161
  • [20] Two antiproliferative seco-4,5-abietane diterpenoids from roots of Salvia ceratophylla L.
    Mirzaei, Hossein Hadavand
    Firuzi, Omidreza
    Chandran, Jima N.
    Schneider, Bernd
    Jassbi, Amir Reza
    PHYTOCHEMISTRY LETTERS, 2019, 29 : 129 - 133