Neferine inhibits angiotensin II-stimulated proliferation in vascular smooth muscle cells through heme oxygenase-1

被引:0
作者
Xiao-chun Li
Guo-xin Tong
Yu Zhang
Shan-xin Liu
Qi-hui Jin
Huai-hong Chen
Peng Chen
机构
[1] the Second Affiliated Hospital,Department of Geratology
[2] School of Medicine,Department of Cardiology
[3] Zhejiang University,Department of Cardiology
[4] the First People's Hospital of Hangzhou,undefined
[5] the First Affiliated Hospital,undefined
[6] School of Medicine,undefined
[7] Zhejiang University,undefined
来源
Acta Pharmacologica Sinica | 2010年 / 31卷
关键词
neferine; heme oxygenase-1; angiotensin II; zinc protoporphyrin; vascular smooth muscle cells; cell proliferation;
D O I
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中图分类号
学科分类号
摘要
引用
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页码:679 / 686
页数:7
相关论文
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  • [1] Touyz RM(2000)Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells Pharmacol Rev 52 639-72
  • [2] Schiffrin EL(2007)Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system Am J Physiol Cell Physiol 292 C82-97
  • [3] Mehta PK(2003)Angiotensin II signaling pathways mediated by tyrosine kinases Int J Biochem Cell Biol 35 780-3
  • [4] Griendling KK(2005)Recent progress in signal transduction research of the angiotensin II type-1 receptor: protein kinases, vascular dysfunction and structural requirement Curr Med Chem Cardiovasc Hematol Agents 3 305-22
  • [5] Yin G(1997)Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells Hypertension 29 334-9
  • [6] Yan C(2005)Carbon monoxide: endogenous production, physiological functions, and pharmacological applications Pharmacol Rev 57 585-630
  • [7] Berk BC(1989)Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite Proc Natl Acad Sci USA 86 99-103
  • [8] Suzuki H(2001)Heme oxygenase-1 protects against vascular constriction and proliferation Nat Med 7 693-8
  • [9] Motley ED(2004)Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1 Circulation 110 1855-60
  • [10] Frank GD(2004)Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection Circulation 110 1296-302