Effect of compound GB-115 on morphine-induced analgesia

被引：0
作者：
L. G. Kolik
V. N. Zhukov
S. B. Seredenin
机构：
[1] Russian Academy of Medical Sciences,Department of Pharmacogenetics, V. V. Zakusov Institute of Pharmacology
来源：
Bulletin of Experimental Biology and Medicine | 2007年 / 143卷
关键词：
antinociception; compound GB-115; morphine; naloxone; mice;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Experiments on outbred mice showed that compound GB-115, a retropeptide analogue of the tetrapeptide cholecystokinin, produced a naloxone-dependent potentiating effect on morphine-induced analgesia in the hot-plate test, but did not modulate animal behavior in the tail-flick test in outbred mice. This potentiation of antinociceptive activity of morphine was probably related to the interaction of GB-115 with supraspinal opioidergic mechanisms.
引用
收藏
页码：703 / 705
页数：2
相关论文
共 50 条
[41]   INBRED STRAIN DIFFERENCES IN MORPHINE-INDUCED ANALGESIA WITH THE HOT PLATE ASSAY - A REASSESSMENT [J].
BELKNAP, JK ;
LAME, M ;
DANIELSON, PW .
BEHAVIOR GENETICS, 1990, 20 (02) :333-338
[42]   Involvement of NOX1/NADPH Oxidase in Morphine-Induced Analgesia and Tolerance [J].
Ibi, Masakazu ;
Matsuno, Kuniharu ;
Matsumoto, Misaki ;
Sasaki, Mika ;
Nakagawa, Takayuki ;
Katsuyama, Masato ;
Iwata, Kazumi ;
Zhang, Jia ;
Kaneko, Shuji ;
Yabe-Nishimura, Chihiro .
JOURNAL OF NEUROSCIENCE, 2011, 31 (49) :18094-18103
[43]   RU 486 reduces morphine-induced analgesia in mice, but steroid receptors are not involved [J].
Bianchi, M ;
Maggi, R ;
Panerai, AE ;
Martini, L .
PHARMACOLOGY, 1996, 52 (06) :387-391
[44]   Potentiation of acute morphine-induced analgesia measured by a thermal test in bone cancer-bearing mice [J].
Gonzalez-Rodriguez, Sara ;
Llames, Sara ;
Hidalgo, Agustin ;
Baamonde, Ana ;
Menendez, Luis .
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2012, 26 (03) :363-372
[45]   Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy In mice [J].
Zarrindast, MR ;
Iraie, F ;
Heidari, MR ;
MohagheghiBadi, M .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 338 (01) :11-16
[46]   Altering dietary levels of protein or vitamins and minerals does not modify morphine-induced analgesia in male rats [J].
Kanarek, RB ;
D'Anci, KE ;
Przypek, JM ;
Mathes, WF .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1999, 62 (02) :203-208
[47]   On the mechanism of tolerance to morphine-induced Straub tail reaction in mice [J].
Zarrindast, MR ;
Alaei-Nia, K ;
Shafizadeh, M .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2001, 69 (3-4) :419-424
[48]   EFFECT OF CYCLOSPORINE-A ON THE MORPHINE-INDUCED PLACE PREFERENCE [J].
SUZUKI, T ;
YOSHIIKE, M ;
FUNADA, M ;
MIZOGUCHI, H ;
KAMEI, J ;
MISAWA, M .
NEUROSCIENCE LETTERS, 1993, 160 (02) :159-162
[49]   Effect of morphine-induced postconditioning in corrections of tetralogy of fallot [J].
Rufang Zhang ;
Li Shen ;
Yewei Xie ;
Lin Gen ;
Xiaobing Li ;
Qiang Ji .
Journal of Cardiothoracic Surgery, 8
[50]   Effect of intravenous alizapride on spinal morphine-induced pruritus [J].
Horta, ML ;
Vianna, PTG .
BRITISH JOURNAL OF ANAESTHESIA, 2003, 91 (02) :287-289
12345