The genome sequence of a novel simian adenovirus in a chimpanzee reveals a close relationship to human adenoviruses

被引：0

作者：

Chenglin Zhou

Hua Tian

Xiaochun Wang

Wei Liu

Shixing Yang

Quan Shen

Yan Wang

Bin Ni

Shengxia Chen

Xingli Fu

Rongmei Fei

Wen Zhang

机构：

[1] Jiangsu University,School of Medical Science and Laboratory Medicine

[2] The First People’s Hospital of Suqian,Department of Laboratory Medicine

[3] Jiangsu Provincial Center for Disease Prevention and Control,Department of Microbiology

[4] University of Pennsylvania Perelman School of Medicine,College of Veterinary Medicine

[5] Nanjing Agricultural University,undefined

来源：

Archives of Virology | 2014年 / 159卷

关键词：

Simian adenovirus; Complete genome; Phylogenetic analysis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Recently, several reports have revealed that some simian adenoviruses (AdVs) strains show a close relationship to human AdVs. In the present study, a simian AdV strain named SAdV-ch1 was detected in chimpanzees in China, and its complete genome was determined. Phylogenetic analysis revealed SAdV-ch1 clustering in a clade that was separate from all of the other simian AdVs but genetically close to a human AdV strain, HAdV-18 (GenBank no. GU191019), sharing 92.5 % sequence identity with it. Recombination analysis provided evidence that a recombination event had occurred between SAdV-ch1 and HAdV-61 (JF964962), where SAdV-ch1 exchanged partial of its hexon gene segment with HAdV-61, leading to the recombinant HAdV-31 (AM749299).

引用

页码：1765 / 1770

页数：5