The genome sequence of a novel simian adenovirus in a chimpanzee reveals a close relationship to human adenoviruses

被引:0
|
作者
Chenglin Zhou
Hua Tian
Xiaochun Wang
Wei Liu
Shixing Yang
Quan Shen
Yan Wang
Bin Ni
Shengxia Chen
Xingli Fu
Rongmei Fei
Wen Zhang
机构
[1] Jiangsu University,School of Medical Science and Laboratory Medicine
[2] The First People’s Hospital of Suqian,Department of Laboratory Medicine
[3] Jiangsu Provincial Center for Disease Prevention and Control,Department of Microbiology
[4] University of Pennsylvania Perelman School of Medicine,College of Veterinary Medicine
[5] Nanjing Agricultural University,undefined
来源
Archives of Virology | 2014年 / 159卷
关键词
Simian adenovirus; Complete genome; Phylogenetic analysis;
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学科分类号
摘要
Recently, several reports have revealed that some simian adenoviruses (AdVs) strains show a close relationship to human AdVs. In the present study, a simian AdV strain named SAdV-ch1 was detected in chimpanzees in China, and its complete genome was determined. Phylogenetic analysis revealed SAdV-ch1 clustering in a clade that was separate from all of the other simian AdVs but genetically close to a human AdV strain, HAdV-18 (GenBank no. GU191019), sharing 92.5 % sequence identity with it. Recombination analysis provided evidence that a recombination event had occurred between SAdV-ch1 and HAdV-61 (JF964962), where SAdV-ch1 exchanged partial of its hexon gene segment with HAdV-61, leading to the recombinant HAdV-31 (AM749299).
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页码:1765 / 1770
页数:5
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