Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential

被引：0

作者：

Fibi Meshrkey

Kelly M. Scheulin

Christopher M. Littlejohn

Joshua Stabach

Bibhuti Saikia

Vedant Thorat

Yimin Huang

Thomas LaFramboise

Edward J. Lesnefsky

Raj R. Rao

Franklin D. West

Shilpa Iyer

机构：

[1] University of Arkansas,Department of Biological Sciences, J. William Fulbright College of Arts and Sciences

[2] University of Arkansas,Cell and Molecular Biology Program

[3] Alexandria University,Department of Histology and Cell Biology, Faculty of Medicine

[4] University of Georgia,Regenerative Bioscience Center

[5] University of Georgia,Department of Animal and Dairy Science

[6] University of Georgia,Neuroscience Program, Biomedical and Health Sciences Institute

[7] Case Western Reserve University School of Medicine,Department of Genetics and Genome Sciences

[8] Virginia Commonwealth University,Department of Physiology and Biophysics

[9] McGuire Veterans Affairs Medical Center,Cardiology Section Medical Service

[10] Virginia Commonwealth University,Department of Biochemistry and Molecular Biology

[11] Virginia Commonwealth University,Division of Cardiology, Department of Internal Medicine, Pauley Heart Center

[12] University of Arkansas,Department of Biomedical Engineering, College of Engineering

来源：

Stem Cell Research & Therapy | / 14卷

关键词：

Mitochondrial disease; hiPSC; Pluripotent stem cell; Reprogramming; Bioenergetics; Respiration; Differentiation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 384 条

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[4] Rao RR(2002)mtLOH (mitochondrial loss of heteroplasmy), aging, and 'surrogate self' Mech Ageing Dev 123 891-898
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