Memory CD4 T cells emerge from effector T-cell progenitors

被引：0

作者：

Laurie E. Harrington

Karen M. Janowski

James R. Oliver

Allan J. Zajac

Casey T. Weaver

机构：

[1] and,Department of Pathology

[2] University of Alabama at Birmingham,Department of Microbiology

[3] 845 19th Street South,undefined

[4] Birmingham,undefined

[5] Alabama 35294,undefined

[6] USA,undefined

[7] Present address: Department of Cell Biology,undefined

[8] University of Alabama at Birmingham,undefined

[9] 845 19th Street South,undefined

[10] Birmingham,undefined

[11] Alabama 35294,undefined

[12] USA.,undefined

来源：

Nature | 2008年 / 452卷

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摘要：

Naive CD4 and CD8 T cells give rise to effector and long-lived memory T cells after activation by antigen. This paper provides evidence that memory CD4 T cells, similar to their CD8 counterparts, differentiate in a linear fashion from effector cells rather than by an alternative differentiation pathway.

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页码：356 / 360

页数：4

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