Memory CD4 T cells emerge from effector T-cell progenitors

被引：0
|
作者：
Laurie E. Harrington
Karen M. Janowski
James R. Oliver
Allan J. Zajac
Casey T. Weaver
机构：
[1] and,Department of Pathology
[2] University of Alabama at Birmingham,Department of Microbiology
[3] 845 19th Street South,undefined
[4] Birmingham,undefined
[5] Alabama 35294,undefined
[6] USA,undefined
[7] Present address: Department of Cell Biology,undefined
[8] University of Alabama at Birmingham,undefined
[9] 845 19th Street South,undefined
[10] Birmingham,undefined
[11] Alabama 35294,undefined
[12] USA.,undefined
来源：
Nature | 2008年 / 452卷
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摘要：
Naive CD4 and CD8 T cells give rise to effector and long-lived memory T cells after activation by antigen. This paper provides evidence that memory CD4 T cells, similar to their CD8 counterparts, differentiate in a linear fashion from effector cells rather than by an alternative differentiation pathway.
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页码：356 / 360
页数：4
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