Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma

被引：0
|
作者：
Jun Li
Shiqiang Zhang
Dingzhun Liao
Qian Zhang
Chujie Chen
Xiangwei Yang
Donggen Jiang
Jun Pang
机构：
[1] Sun Yat-sen University,Department of Urology, Kidney and Urology Center, The Seventh Affiliated Hospital
[2] Sun Yat-sen University,Department of Pathology, The Seventh Affiliated Hospital
[3] Sun Yat-sen University,Department of Rehabilitation Medicine, The Seventh Affiliated Hospital
来源：
BMC Cancer | / 22卷
关键词：
Renal cell carcinoma; PFKFB3; Glycolysis; Proliferation; G1/S transition;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
    Kovacs, Laszlo
    Cao, Yapeng
    Han, Weihong
    Meadows, Louise
    Kovacs-Kasa, Anita
    Kondrikov, Dmitry
    Verin, Alexander D.
    Barman, Scott A.
    Dong, Zheng
    Huo, Yuqing
    Su, Yunchao
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 200 (05) : 617 - 627
  • [42] Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation
    Cheng, Xiao
    Jia, Xiupeng
    Wang, Chunnian
    Zhou, Shangyan
    Chen, Jiayi
    Chen, Lei
    Chen, Jinping
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2023, 21 (01)
  • [43] A Potential Oncogenic Role for PFKFB3 Overexpression in Gastric Cancer Progression
    Lei, Lan
    Hong, Lian-Lian
    Ling, Zhe-Nan
    Zhong, Yi
    Hu, Xuan-Yu
    Li, Pei
    Ling, Zhi-Qiang
    CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 2021, 12 (07)
  • [44] Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation
    Duran, Joan
    Gomez, Marta
    Navarro-Sabate, Aurea
    Riera-Sans, Lluis
    Obach, Merce
    Manzano, Anna
    Perales, Jose C.
    Bartrons, Ramon
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 367 (04) : 748 - 754
  • [45] Hexokinase 2 overexpression promotes the proliferation and survival of laryngeal squamous cell carcinoma
    Chen, Jian
    Zhang, Sulin
    Li, Yuncheng
    Tang, Zhengang
    Kong, Weijia
    TUMOR BIOLOGY, 2014, 35 (04) : 3743 - 3753
  • [46] PFK15, a PFKFB3 antagonist, inhibits autophagy and proliferation in rhabdomyosarcoma cells
    Wang, Chunhui
    Qu, Jianghong
    Yan, Siyuan
    Gao, Quan
    Hao, Sibin
    Zhou, Dongsheng
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 42 (01) : 359 - 367
  • [47] mTOR up-regulation of PFKFB3 is essential for acute myeloid leukemia cell survival
    Feng, Yonghuai
    Wu, Liusong
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 483 (02) : 897 - 903
  • [48] Targeting T Cell Metabolism as a Novel Approach for Treatment of MS: With a Focus on PFKFB3 Inhibitors
    Vakili, Mahsa Eshkevar
    Mohammadi, Fateme Nezhad Shah
    Ataollahi, Mohammad Reza
    Shams, Keivan
    Eklund, Kari K.
    Daryabor, Gholamreza
    Kalantar, Kurosh
    ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2023, 23 (04) : 417 - 422
  • [49] Long non-coding RNA MSC-AS1 facilitates the proliferation and glycolysis of gastric cancer cells by regulating PFKFB3 expression
    Jin, Xianzhen
    Qiao, Lina
    Fan, Hui
    Liao, Chunyan
    Zheng, Jianbao
    Wang, Wei
    Ma, Xiuqin
    Yang, Min
    Sun, Xuejun
    Zhao, Wei
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2021, 18 (02): : 546 - 554
  • [50] PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesis
    Peng, Fang
    Li, Qiang
    Sun, Jia-Yuan
    Luo, Ying
    Chen, Ming
    Bao, Yong
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 52 (03) : 945 - 954
12345