Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma

被引:0
|
作者
Jun Li
Shiqiang Zhang
Dingzhun Liao
Qian Zhang
Chujie Chen
Xiangwei Yang
Donggen Jiang
Jun Pang
机构
[1] Sun Yat-sen University,Department of Urology, Kidney and Urology Center, The Seventh Affiliated Hospital
[2] Sun Yat-sen University,Department of Pathology, The Seventh Affiliated Hospital
[3] Sun Yat-sen University,Department of Rehabilitation Medicine, The Seventh Affiliated Hospital
来源
BMC Cancer | / 22卷
关键词
Renal cell carcinoma; PFKFB3; Glycolysis; Proliferation; G1/S transition;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] USP3 promotes clear cell renal cell carcinoma progression by stabilizing MYC and enhancing glycolysis
    Xiao, Zhiliang
    Wang, Yuan
    Pan, Dehua
    Liu, Xin
    Gan, Jin
    Huang, Liang
    Feng, Yan
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2025, 1869 (06):
  • [42] Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
    Yang, Kaiying
    Qiu, Tong
    Zhou, Jiangyuan
    Gong, Xue
    Zhang, Xuepeng
    Lan, Yuru
    Zhang, Zixin
    Ji, Yi
    JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 21 (01)
  • [43] CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma
    Cai, Le
    Wang, He
    Yang, Qing
    ONCOLOGY LETTERS, 2017, 13 (01) : 51 - 56
  • [44] SUMOylated hnRNPM suppresses PFKFB3 phosphorylation to regulate glycolysis and tumorigenesis
    Zhong, Ya-Xian
    Zhao, Huan-Bin
    Lian, Meng-Han
    Shen, Jia-Ming
    Li, Cheng-Xiao
    Ma, Hong-Ming
    Xu, Dan
    Chen, Guo-Qiang
    Zhang, Cheng
    CANCER LETTERS, 2025, 616
  • [45] TRIM28 Regulates Hepatocellular Carcinoma Progression and Aerobic Glycolysis through Interacting with PFKFB3
    Zeng, Lei
    Zhou, Kexiang
    Yang, Hong
    Guo, Peng
    Zhu, Yumin
    Ding, Jun
    Bie, Ping
    Zhang, Zhiqing
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2023, 37 (02): : 951 - 959
  • [46] Inhibition of stromal glycolysis by targeting PFKFB3 decreases experimental colitis
    Zhou, Z.
    Plug, L. G.
    de Jonge-Muller, E. S. M.
    Abou Elmagd, A.
    van der Meulen-de Jong, A. E.
    Barnhoorn, M. C.
    Hawinkels, L. J. A. C.
    JOURNAL OF CROHNS & COLITIS, 2022, 16 : I150 - I150
  • [47] Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
    Kaiying Yang
    Tong Qiu
    Jiangyuan Zhou
    Xue Gong
    Xuepeng Zhang
    Yuru Lan
    Zixin Zhang
    Yi Ji
    Journal of Translational Medicine, 21
  • [48] miR-27a promotes cell proliferation and metastasis in renal cell carcinoma
    Peng, Hongjun
    Wang, Xianjun
    Zhang, Pei
    Sun, Tao
    Ren, Xianguo
    Xia, Zhengkun
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (02): : 2259 - 2266
  • [49] Correction to: PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma
    Prabhu Thirusangu
    Upasana Ray
    Sayantani Sarkar Bhattacharya
    Derek B. Oien
    Ling Jin
    Julie Staub
    Nagarajan Kannan
    Julian R. Molina
    Viji Shridhar
    Oncogene, 2023, 42 : 79 - 82
  • [50] Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation
    Duran, Joan
    Gomez, Marta
    Navarro-Sabate, Aurea
    Riera-Sans, Lluis
    Obach, Merce
    Manzano, Anna
    Perales, Jose C.
    Bartrons, Ramon
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 367 (04) : 748 - 754