Prion strain discrimination using luminescent conjugated polymers

被引:0
|
作者
Christina J Sigurdson
K Peter R Nilsson
Simone Hornemann
Giuseppe Manco
Magdalini Polymenidou
Petra Schwarz
Mario Leclerc
Per Hammarström
Kurt Wüthrich
Adriano Aguzzi
机构
[1] UniversitätsSpital Zürich,Department of Pathology
[2] Institute of Neuropathology,Department of Chemistry
[3] Institut für Molekularbiologie und Biophysik,Department of Chemistry
[4] ETH Zürich,Department of Molecular Biology and Skaggs Institute for Chemical Biology
[5] Vachon Building,undefined
[6] Rue de la Médecine,undefined
[7] Université Laval,undefined
[8] Linköping University,undefined
[9] The Scripps Research Institute,undefined
来源
Nature Methods | 2007年 / 4卷
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摘要
Improved photostability of fluorescent proteins would benefit many applications but is usually an afterthought in selection screens. Setting photostability as the primary selection criterion in screens for improved fluorescent proteins yielded highly photostable variants of existing orange and red fluorescent proteins without compromising other beneficial characteristics.
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页码:1023 / 1030
页数:7
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