Prediction of Warfarin Maintenance Dose in Han Chinese Patients Using a Mechanistic Model Based on Genetic and Non-Genetic Factors

被引：0
作者：
Yuan Lu
Jinbo Yang
Haiyan Zhang
Jin Yang
机构：
[1] China Pharmaceutical University,Center of Drug Metabolism and Pharmacokinetics
[2] State Food and Drug Administration,Center for Drug Evaluation
[3] Affiliated Wujin Hospital of Jiangsu University,Department of Pharmacy
来源：
Clinical Pharmacokinetics | 2013年 / 52卷
关键词：
Warfarin; International Normalize Ratio; Warfarin Dose; CYP2C9 Genotype; Enzyme Kinetic Parameter;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
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页码：567 / 581
页数：14
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  • [1] Daly AK(2003)Pharmacogenetics of oral anticoagulants Pharmacogenetics 13 247-252
  • [2] King BP(2008)Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin Clin Pharmacol Ther 84 326-331
  • [3] Gage BF(2012)The population pharmacokinetics of Br J Clin Pharmacol 73 66-76
  • [4] Eby C(2008)- and N Engl J Med 358 999-1008
  • [5] Johnson JA(2007)-warfarin: effect of genetic and clinical factors Pharmacogenomics J 7 99-111
  • [6] Lane S(2008)Genetic determinants of response to warfarin during initial anticoagulation Blood 112 1022-1027
  • [7] Al-Zubiedi S(2003)Pharmacogenetics of warfarin: current status and future challenges Semin Vasc Med 3 221-230
  • [8] Hatch E(1997)A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose Pharmacol Ther 73 67-74
  • [9] Schwarz UI(2001)Warfarin and other coumarin derivatives: pharmacokinetics, pharmacodynamics, and drug interactions Clin Pharmacokinet 40 587-603
  • [10] Ritchie MD(1997)Human P450 metabolism of warfarin J Biol Chem 272 29068-29075
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