Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

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作者
Jesús Madero-Pérez
Elena Fdez
Belén Fernández
Antonio J. Lara Ordóñez
Marian Blanca Ramírez
Patricia Gómez-Suaga
Dieter Waschbüsch
Evy Lobbestael
Veerle Baekelandt
Angus C. Nairn
Javier Ruiz-Martínez
Ana Aiastui
Adolfo López de Munain
Pawel Lis
Thomas Comptdaer
Jean-Marc Taymans
Marie-Christine Chartier-Harlin
Alexandria Beilina
Adriano Gonnelli
Mark R. Cookson
Elisa Greggio
Sabine Hilfiker
机构
[1] Institute of Parasitology and Biomedicine “López-Neyra”,Department of Experimental Tumorbiology
[2] Consejo Superior de Investigaciones Científicas (CSIC),Laboratory for Neurobiology and Gene Therapy
[3] Westfälische Wilhelms University Münster,Department of Psychiatry
[4] KU Leuven,Division of Neurosciences
[5] Yale University School of Medicine,Cell Culture Platform and Division of Neurosciences
[6] Instituto Biodonostia-CIBERNED,Division of Neurosciences, Instituto Biodonostia
[7] Instituto Biodonostia,CIBERNED
[8] University of the Basque Country UPV-EHU,Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences
[9] University of Dundee,Department of Biology
[10] University of Lille,undefined
[11] Inserm,undefined
[12] CHU Lille,undefined
[13] UMR-S 1172 - JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer,undefined
[14] Cell Biology and Gene Expression Section,undefined
[15] Laboratory of Neurogenetics,undefined
[16] National Institute on Aging,undefined
[17] National Institutes of Health,undefined
[18] University of Padova,undefined
关键词
Centrosome; LRRK2; Parkinson’s disease; Phosphorylation; Rab8a;
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