Ischaemic heart disease during pregnancy or post-partum: systematic review and case series

被引:0
作者
H. Lameijer
M.A.M. Kampman
M.A. Oudijk
P.G. Pieper
机构
[1] University Medical Centre Groningen,Department of Cardiology
[2] University of Groningen,Department of Emergency Medicine
[3] University Medical Centre Groningen,Department of Obstetrics
[4] University of Groningen,undefined
[5] The Netherlands Heart Institute (ICIN),undefined
[6] University Medical Centre Utrecht,undefined
[7] University of Utrecht,undefined
来源
Netherlands Heart Journal | 2015年 / 23卷
关键词
Ischemic heart disease; Pregnancy; Maternal;
D O I
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学科分类号
摘要
The risk of manifestations of ischaemic heart disease (IHD) in fertile women is elevated during pregnancy and the post-partum period. With increasing maternal age and a higher prevalence of cardiac risk factors, the incidence of IHD during pregnancy is rising. However, information in the literature is scarce. We therefore performed a retrospective cohort study and systematically reviewed the overall (1975–2013) and contemporary (2005–2013) literature concerning IHD presenting during pregnancy or in the post-partum period. We report two cases of IHD with atypical presentation during pregnancy or post-partum. In our review, we describe 146 pregnancies, including 57 contemporary cases (2005–2013). Risk factors for IHD were present in 80 %. Of the cases of IHD, 71 % manifested in the third trimester or the post-partum period, and 95 % presented with chest pain. The main cause was coronary dissection (35 %), or thrombus/emboli (35 %) in the more contemporary group. Maternal mortality was 8 % (6 % in the contemporary group), and the main cardiac complication was ventricular tachycardia (n = 17). Premature delivery rate was 56 %, and caesarean section was performed in 57 %. Perinatal mortality was 4 %. In conclusion, IHD during pregnancy or in the post-partum period has high maternal mortality and morbidity rates. Also, premature delivery and perinatal mortality rates are high.
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页码:249 / 257
页数:8
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