Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder

被引：0
|
作者：
J. Pauls
B. Bandelow
E. Rüther
J. Kornhuber
机构：
[1] Department of Psychiatry,
[2] University of Göttingen,undefined
[3] Federal Republic of Germany,undefined
来源：
Journal of Neural Transmission | 2000年 / 107卷
关键词：
Keywords: Genetic, association, affective disorders, angiotensin converting enzyme, insertion/deletion polymorphism, mood disorders.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The insertion/deletion polymorphism of the gene of angiotensin-converting enzyme (ACE) was investigated in a case-control study including 169 patients with suffering from either bipolar disorder type I or unipolar recurrent major depression (DSM-IV) and 169 healthy controls. No significant association was found with bipolar disorder type I or unipolar recurrent depression and the polymorphism of the ACE gene. A previously reported genetic association (Arinami et al., 1996) was not confirmed by the present study.
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页码：1361 / 1366
页数：5
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