The prevalence of dyslipidemia in patients with diabetes mellitus of ayurveda Hospital

被引：33

作者：

Dixit A.K. ^{[1
]}

Dey R. ^{[1
]}

Suresh A. ^{[1
]}

Chaudhuri S. ^{[1
]}

Panda A.K. ^{[2
]}

Mitra A. ^{[2
]}

Hazra J. ^{[2
]}

机构：

[1] Department of Pathology and Biochemistry, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata, West Bengal

[2] Hospital Division, National Research Institute of Ayurvedic Drug Development, Department of AYUSH, Government of India, 4 CN Block, Sec-5, Bidhannagar, Kolkata, West Bengal

来源：

Journal of Diabetes & Metabolic Disorders | / 13卷 / 1期

关键词：

Blood sugar; Diabetes mellitus; Dyslipidemia; Hyperlipidemia; Lipid profile;

D O I：

10.1186/2251-6581-13-58

中图分类号：

学科分类号：

摘要：

Background: Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. Early detection and treatment of dyslipidemia in type-2 diabetes mellitus can prevent risk for atherogenic cardiovascular disorder. The rationale of this study was to detect the lipid abnormality in diabetic patients.Methods: Necessary data was collected from the medical archives of 150 patients (73 female and 77 male) with diabetes mellitus registered in Department of pathology and biochemistry of a Ayurveda hospital established at Kolkata, India.Results: The mean ages of female and male subjects were 51.8 ± 10.8 and 53.2 ± 11.3 years respectively. The range and mean value of FBS in females were 113-342 mg/dl and 157.7 ± 6.3 mg/dl, while the range and mean value of PPBS in females were 135-560 mg/dl and 275.5 ± 12.3 mg/dl respectively. Results showed that range and mean value of FBS in males were 111-462 mg/dl and 160.8 ± 7.4 mg/dl, while the range and mean value of PPBS in males were 136-598 mg/dl and 302.1 ± 12.6 mg/dl respectively. Results of serum lipids showed that the mean values for total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) in female patients were 202.2 ± 5.9 mg/dl, 168.3 ± 8.2 mg/dl, 44.9 ± 1.3 mg/dl, 123.6 ± 5.2 mg/dl and 33.7 ± 1.7 mg/dl respectively. The mean values for TC, TG, HDL-C, LDL-C and VLDL-C in male patients were 182.5 ± 4.8 mg/dl, 128.1 ± 10.8 mg/dl, 40.8 ± 1.2 mg/dl, 105.4 ± 4.8 mg/dl and 36.2 ± 2.2 respectively. FBS showed significant positive correlation with PPBS, cholesterol, TG, and VLDL-C. PPBS also demonstrated direct and significant correlations with TG and VLDL-C.Conclusions: The study showed common lipid abnormalities during diabetes induced dyslipidemia i.e., hypercholesterolemia, hypertriglyceridemia and elevated LDL-C. This study suggests the dominance of hyperlipidemia over increased prevalence of dyslipidemia. © 2014 Dixit et al.; licensee BioMed Central Ltd.

引用

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