Bifunctional derivatives of β-adrenoreceptor modulators in chromatography-mass spectrometry

被引:0
作者
A. A. Samosorova
Yu. A. Efimova
I. V. Rybal’chenko
机构
[1] Moscow State University of Fine Chemical Technology,
[2] 27 Scientific Center of the Ministry of Defense of the Russian Federation,undefined
来源
Journal of Analytical Chemistry | 2015年 / 70卷
关键词
gas chromatography-mass spectrometry; β-adrenoreceptor modulators; β-blockers; β-agonists; preparation of bifunctional derivatives;
D O I
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中图分类号
学科分类号
摘要
Results of a comparative study of methods of derivatization for the determination of β-blockers and β-agonists by gas chromatography-mass spectrometry have been presented. The efficiency of the best method has been confirmed by an example of a GC-MS analysis of a mixture of 13 β-adrenoreceptor modulators after the preparation of corresponding bifunctional derivatives.
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页码:488 / 494
页数:6
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