Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

被引:0
|
作者
Bernardo Sgarbi Reis
Aneta Rogoz
Frederico Azevedo Costa-Pinto
Ichiro Taniuchi
Daniel Mucida
机构
[1] Laboratory of Mucosal Immunology,Department of Pathology
[2] The Rockefeller University,undefined
[3] School of Veterinary Medicine,undefined
[4] University of Sao Paulo,undefined
[5] Laboratory for Transcriptional Regulation,undefined
[6] RIKEN Research Center for Allergy and Immunology,undefined
来源
Nature Immunology | 2013年 / 14卷
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摘要
CD4+ and CD8+ T cells are considered distinct functional lymphocyte subsets. Cheroutre and Mucida and their colleagues show that mature gut-associated CD4+ T cells lose ThPOK expression and reactivate CD8 cytolytic effector programs.
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页码:271 / 280
页数:9
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