Preparation and in Vitro/in Vivo Evaluation of Insulin-Loaded Poly(Acryloyl-Hydroxyethyl Starch)-PLGA Composite Microspheres

被引：0
作者：
Ge Jiang
Wei Qiu
Patrick P. DeLuca
机构：
[1] University of Kentucky ,Pharmaceutical Sciences
[2] College of Pharmacy,undefined
来源：
Pharmaceutical Research | 2003年 / 20卷
关键词：
PLGA; hydroxyethyl starch; microsphere; insulin; controlled release;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The purpose of this study was to develop and evaluate a novel composite microsphere delivery system composed of poly(D,L-lactide-co-glycolide) (PLGA) and poly(acryloyl hydroxyethyl starch) (acryloyl derivatized HES; AcHES) hydrogel using bovine insulin as a model therapeutic protein.
引用
收藏
页码：452 / 459
页数：7
相关论文
共 126 条
[91]  
Tanigawara Y.(undefined)undefined undefined undefined undefined-undefined
[92]  
Ogawa Y.(undefined)undefined undefined undefined undefined-undefined
[93]  
Togu#x03A7; H.(undefined)undefined undefined undefined undefined-undefined
[94]  
Igartua M.(undefined)undefined undefined undefined undefined-undefined
[95]  
Hernandez R. M.(undefined)undefined undefined undefined undefined-undefined
[96]  
Esquisabel A.(undefined)undefined undefined undefined undefined-undefined
[97]  
Gascon A. R.(undefined)undefined undefined undefined undefined-undefined
[98]  
Calvo M. B.(undefined)undefined undefined undefined undefined-undefined
[99]  
Pedraz J. L.(undefined)undefined undefined undefined undefined-undefined
[100]  
Soriano I.(undefined)undefined undefined undefined undefined-undefined
45678910111213