Cervical Dedifferentiated Liposarcoma with Meningothelial-Like Whorling

被引：8

作者：

Jeffrey M. Blumberg

Jaroslaw Jedrych

Jose Costa

Benjamin Judson

机构：

[1] Yale Otolaryngology, New Haven, CT, 06519, Yale Physicians Building, 800 Howard Avenue

[2] Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520-8023, P.O. Box 208023, 310 Cedar Street

来源：

Head and Neck Pathology | 2012年 / 6卷 / 4期

关键词：

Cervical; Dedifferentiated; Liposarcoma; Meningothelial-like whorls;

D O I：

10.1007/s12105-012-0354-7

中图分类号：

学科分类号：

摘要：

Liposarcomas are the most common soft-tissue sarcoma of adults, but rare in the head and neck. Recently, a subtype of dedifferentiated liposarcoma with meningiothelial-like whorls was reported and we present the first description of such a tumor in the head and neck. A 65 year old male underwent a resection of a calcified retroesophageal mass that was in close relation to the left hemithyroid and recurrent laryngeal nerve. It was resected en bloc with the left thyroid lobe. Initial pathologic evaluation suggested the mass was a schwanomma of the recurrent laryngeal nerve, but positive staining for MDM2 and CDK4 indicated the tumor was a dedifferentiated liposarcoma. Further evaluation elucidated the unique meningothelial-like whorls within the tumor. This case demonstrates dedifferentiated liposarcomas do appear in the head and neck. Furthermore, this is the first report in the head and neck of the mengiothelial-like whorling pattern type of dedifferentiated liposarcoma. © 2012 Springer Science+Business Media, LLC.

引用

页码：476 / 480

页数：4

共 18 条

[11]

Li C., Liu L., Liu D.L., Dedifferentiated liposarcoma with meningothelial-like whorls, Zhonghua Bing Li Xue Za Zhi Chinese Journal of Pathology, 34, 6, (2005)

[12]

Evans H.L., Liposarcoma: a study of 55 cases with a reassessment of its classification, Am J Surg Pathol, 3, 6, pp. 507-523, (1979)

[13]

Gritli S., Khamassi K., Lachkhem A., Et al., Head and neck liposarcomas: a 32 years experience, Auris Nasus Larynx, 37, 3, pp. 347-351, (2010)

[14]

Dalal K.M., Antonescu C.R., Singer S., Diagnosis and management of lipomatous tumors, J Surg Oncol, 97, 4, pp. 298-313, (2008)

[15]

Dalal K.M., Kattan M.W., Antonescu C.R., Brennan M.F., Singer S., Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk, Ann Surg, 244, 3, pp. 381-391, (2006)

[16]

de la Rosa G., Barredes S., Aisner S., Dedifferentiated liposarcoma of the cheek, Ann Diagn Pathol, 8, 5, pp. 352-357, (2004)

[17]

Rogers J., Pattl Y., Strickland-Marmol L., Padhya T., Lipomatous tumors of the parapharyngeal space: case series and literature review, Arch Otolaryngol Head Neck Surg, 136, 6, pp. 621-624, (2010)

[18]

Fanburg-Smith J.C., Furlong M.A., Childers E.L.B., Liposarcoma of the oral and salivary gland region: A clinicopathologic study of 18 cases with emphasis on specific sites, morphologic subtypes, and clinical outcome, Mod Pathol, 15, 10, pp. 1020-1031, (2002)

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