Improved fluid management utilizing humidified incubators in extremely low birth weight infants

被引:21
作者
Gaylord M.S. [1 ]
Wright K. [1 ]
Lorch K. [2 ]
Lorch V. [1 ]
Walker E. [3 ]
机构
[1] University of Tennessee, Graduate School of Medicine, Knoxville, TN
[2] Emory University, Atlanta, GA
[3] Department of Statistics, University of Tennessee, Knoxville, TN
关键词
D O I
10.1038/sj.jp.7210561
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学科分类号
摘要
Objective: To compare fluid and electrolyte management in extremely low birth weight (ELBW) infants nursed in humidified versus nonhumidified incubators. Study Design: Setting - tertiary intensive care nursery. Subjects - all infants with birth weight < 1000 g admitted 1/95 to 1/99 who were treated with incubators and survived for >96 hours (N = 155). Intervention - retrospective comparison of daily weights, fluid intakes, urine outputs, and serum electrolytes between group 1 (n = 70, nonhumidified incubators, born 1/95 to 1/97) and group 2 (n = 85, humidified incubators, born 1/97 to 1/99) over the first 4 days after birth. Results: Despite similar daily weight losses between groups, group 1 infants received higher fluid intakes, had lower urine outputs, and had a higher incidence of hypernatremia, hyperkalemia, and azotemia (p < 0.05). Although no differences in mortality or the incidence of patent ductus arteriosus, bronchopulmonary dysplasia, or the overall rate of nosocomial infections were observed, the proportion of gram-negative isolates increased significantly (62%, p < 0.05) following the introduction of humidified incubators. Conclusions: ELBW weight infants nursed in humidified incubators have lower fluid requirements, improved electrolyte balance, and higher urine outputs during the first 4 days after birth compared to those nursed in nonhumidified incubators.
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页码:438 / 443
页数:5
相关论文
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