A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer

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作者
Kerry Lynn Reynolds
Philippe L. Bedard
Se-Hoon Lee
Chia-Chi Lin
Josep Tabernero
Maria Alsina
Ezra Cohen
José Baselga
George Blumenschein
Donna M. Graham
Ignacio Garrido-Laguna
Dejan Juric
Sunil Sharma
Ravi Salgia
Abdelkader Seroutou
Xianbin Tian
Rose Fernandez
Alex Morozov
Qing Sheng
Thiruvamoor Ramkumar
Angela Zubel
Yung-Jue Bang
机构
[1] Massachusetts General Hospital,Vall d’Hebron University Hospital and Institute of Oncology (VHIO)
[2] Princess Margaret Cancer Centre,Moores Cancer Center
[3] Seoul National University College of Medicine,Department of Thoracic/Head and Neck Medical Oncology
[4] National Taiwan University Hospital,undefined
[5] Universitat Autònoma de Barcelona,undefined
[6] University of California at San Diego,undefined
[7] Memorial Sloan Kettering Cancer Center,undefined
[8] The University of Texas MD Anderson Cancer Center,undefined
[9] Huntsman Cancer Institute,undefined
[10] University of Chicago,undefined
[11] Novartis Pharma AG,undefined
[12] Novartis Pharmaceuticals Corporation,undefined
[13] Novartis Institutes for BioMedical Research,undefined
[14] City of Hope,undefined
[15] Department of Medical Oncology and Therapeutics Research,undefined
[16] Pfizer Inc.,undefined
来源
BMC Cancer | / 17卷
关键词
Phase I; HER3; HER2; Monoclonal antibody; LJM716;
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