The effects of the selective 5-HT2C receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats

[1] Abramowski D(1995)Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera Neuropharmacology 34 1635-1645

[2] Rigo M(2005)Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs Neuroscience 133 983-997

[3] Duc D(2006)Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex J Neurosci 26 13264-13272

[4] Hoyer D(2001)Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635 Int J Neuropsychopharmacol 4 399-408

[5] Staufenbiel M(1998)mCPP-induced anxiety in the light-dark box in rats—a new method for screening anxiolytic activity Psychopharmacology (Berl) 136 291-298

[6] Abrams JK(1997)6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist J Med Chem 40 3494-3496

[7] Johnson PL(2004)The effects of chronic treadmill and wheel running on behavior in rats Brain Res 1019 84-96

[8] Hay-Schmidt A(2007)Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist Biol Psychiatry 62 1111-1118

[9] Mikkelsen JD(2003)Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment Brain Res 993 1-9

[10] Shekhar A(2000)Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS Neuropharmacology 39 123-132

[1] Abramowski D(1995)Localization of the 5-hydroxytryptamine2C receptor protein in human and rat brain using specific antisera Neuropharmacology 34 1635-1645

[2] Rigo M(2005)Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs Neuroscience 133 983-997

[3] Duc D(2006)Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex J Neurosci 26 13264-13272

[4] Hoyer D(2001)Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635 Int J Neuropsychopharmacol 4 399-408

[5] Staufenbiel M(1998)mCPP-induced anxiety in the light-dark box in rats—a new method for screening anxiolytic activity Psychopharmacology (Berl) 136 291-298

[6] Abrams JK(1997)6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist J Med Chem 40 3494-3496

[7] Johnson PL(2004)The effects of chronic treadmill and wheel running on behavior in rats Brain Res 1019 84-96

[8] Hay-Schmidt A(2007)Acute selective serotonin reuptake inhibitors increase conditioned fear expression: blockade with a 5-HT(2C) receptor antagonist Biol Psychiatry 62 1111-1118

[9] Mikkelsen JD(2003)Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment Brain Res 993 1-9

[10] Shekhar A(2000)Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS Neuropharmacology 39 123-132