Human liver stem cells attenuate concanavalin A-induced acute liver injury by modulating myeloid-derived suppressor cells and CD4+ T cells in mice

被引：0
|
作者：
Yanzhen Bi
Jiannan Li
Yonghong Yang
Quanyi Wang
Quanquan Wang
Xiaobei Zhang
Guanjun Dong
Yibo Wang
Zhongping Duan
Zhenfeng Shu
Tongjun Liu
Yu Chen
Kai Zhang
Feng Hong
机构：
[1] Beijing Youan Hospital,Beijing Artificial Liver Treatment & Training Center
[2] Captial Medical University,Department of General Surgery
[3] The Second Hospital of Jilin University,Institute of Liver Diseases
[4] Affiliated Hospital of Jining Medical University,Department of Neuromuscular Disease
[5] The Third Hospital of Hebei Medical University,Institute of Immunology and Molecular Medicine
[6] Jining Medical University,undefined
[7] Shanghai Meifeng Biotechnology Co.,undefined
[8] Ltd,undefined
来源：
Stem Cell Research & Therapy | / 10卷
关键词：
Acute liver injury; Human liver stem cells; MDSCs; CD4; T cells; Concanavalin A;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Myeloid-Derived Suppressor Cells Induce Exhaustion- Like CD8+ T Cells during JEV Infection
    Zhang, Weijia
    Yu, Qing
    Gao, Xiaochen
    Chen, Haowei
    Su, Jie
    Chen, Yanru
    Li, Yanling
    Zhang, Nan
    Fu, Zhenfang
    Cui, Min
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2024, 20 (15): : 5959 - 5978
  • [22] Critical Role of Myeloid-Derived Suppressor Cells in Tumor-Induced Liver Immune Suppression through Inhibition of NKT Cell Function
    Zhang, Hongru
    Li, Zheng
    Wang, Li
    Tian, Gaofei
    Tian, Jun
    Yang, Zishan
    Cao, Guangchao
    Zhou, Hong
    Zhao, Liqing
    Wu, Zhenzhou
    Yin, Zhinan
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [23] High Levels of BMP2 Promote Liver Cancer Growth via the Activation of Myeloid-Derived Suppressor Cells
    Wu, Gui
    Huang, Fei
    Chen, Yaoqing
    Zhuang, Yuehong
    Huang, Yunpeng
    Xie, Yun
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [24] CD24 aggravates acute liver injury in autoimmune hepatitis by promoting IFN-γ production by CD4+ T cells
    Zheng, Chenhong
    Yin, Shulei
    Yang, Yang
    Yu, Yizhi
    Xie, Xiaohua
    CELLULAR & MOLECULAR IMMUNOLOGY, 2018, 15 (03) : 260 - 271
  • [25] Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
    Cassetta, Luca
    Baekkevold, Espen S.
    Brandau, Sven
    Bujko, Anna
    Cassatella, Marco A.
    Dorhoi, Anca
    Krieg, Carsten
    Lin, Ang
    Lore, Karin
    Marini, Olivia
    Pollard, Jeffrey W.
    Roussel, Mikael
    Scapini, Patrizia
    Umansky, Viktor
    Adema, Gosse J.
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2019, 68 (04) : 687 - 697
  • [26] Tumor Induced Hepatic Myeloid Derived Suppressor Cells Can Cause Moderate Liver Damage
    Eggert, Tobias
    Medina-Echeverz, Jose
    Kapanadze, Tamar
    Kruhlak, Michael J.
    Korangy, Firouzeh
    Greten, Tim F.
    PLOS ONE, 2014, 9 (11):
  • [27] Anti-CD24 neutralizing antibody exacerbates Concanavalin A-induced acute liver injury in mice via liver M1 macrophages
    Liu, Hongyu
    Hai, Lei
    Tian, Jingqi
    Xiang, Jie
    Fan, Yatong
    Zhang, Hua
    Liu, Jianhui
    Zhang, Xuejun
    IMMUNOLOGY LETTERS, 2017, 181 : 87 - 93
  • [28] Involvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome
    Zhu, Mengting
    Xu, Yuping
    Li, Caihua
    Lu, Zhimin
    Bi, Kaihuan
    Wang, Kangxia
    Guo, Peipei
    Jiang, Huanhuan
    Cao, Yunxia
    REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2021, 19 (01)
  • [29] HPV-associated head and neck cancer is characterized by distinct profiles of CD8+ T cells and myeloid-derived suppressor cells
    Benjamin A. Kansy
    Tim P. Wehrs
    Kirsten Bruderek
    Yu Si
    Sonja Ludwig
    Freya Droege
    Pia Hasskamp
    Uta Henkel
    Nina Dominas
    Thomas K. Hoffmann
    Peter A. Horn
    Martin Schuler
    Thomas C. Gauler
    Monika Lindemann
    Stephan Lang
    Agnes Bankfalvi
    Sven Brandau
    Cancer Immunology, Immunotherapy, 2023, 72 : 4367 - 4383
  • [30] Involvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome
    Mengting Zhu
    Yuping Xu
    Caihua Li
    Zhimin Lu
    Kaihuan Bi
    Kangxia Wang
    Peipei Guo
    Huanhuan Jiang
    Yunxia Cao
    Reproductive Biology and Endocrinology, 19
12345