The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

被引:0
|
作者
Zachary Gerhart-Hines
Dan Feng
Matthew J. Emmett
Logan J. Everett
Emanuele Loro
Erika R. Briggs
Anne Bugge
Catherine Hou
Christine Ferrara
Patrick Seale
Daniel A. Pryma
Tejvir S. Khurana
Mitchell A. Lazar
机构
[1] Diabetes,Division of Endocrinology, Department of Medicine, Department of Genetics
[2] and Metabolism,Department of Physiology
[3] Perelman School of Medicine at the University of Pennsylvania,Department of Radiology
[4] The Institute for Diabetes,Department of Pediatrics
[5] Obesity,Department of Cell and Developmental Biology
[6] and Metabolism,undefined
[7] Perelman School of Medicine at the University of Pennsylvania,undefined
[8] Perelman School of Medicine at the University of Pennsylvania,undefined
[9] Pennsylvania Muscle Institute,undefined
[10] Perelman School of Medicine at the University of Pennsylvania,undefined
[11] Perelman School of Medicine at the University of Pennsylvania,undefined
[12] Children’s Hospital of Philadelphia,undefined
[13] Perelman School of Medicine at the University of Pennsylvania,undefined
来源
Nature | 2013年 / 503卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The nuclear receptor Rev-erbα, a powerful repressor of transcription, is shown to link circadian and thermogenic networks by regulating the function of brown adipose tissue.
引用
收藏
页码:410 / 413
页数:3
相关论文
共 50 条
  • [31] The role of the orphan nuclear receptor Rev-erbα in adipocyte differentiation and function
    Laitinen, S
    Fontaine, C
    Fruchart, JC
    Staels, B
    BIOCHIMIE, 2005, 87 (01) : 21 - 25
  • [32] The Nuclear Receptor REV-ERBα Alters Mood and Neurotransmission in the Prefrontal Cortex
    Otsuka, Tsuyoshi
    Kohsaka, Akira
    Hue Thi Le
    Nakao, Tomomi
    Thein, Zaw Lin
    Maeda, Masanobu
    FASEB JOURNAL, 2017, 31
  • [33] Regulation of BCRP expression and sulfasalazine pharmacokinetics by the nuclear receptor REV-ERBα
    Wu, Chunhong
    Xiao, Yifei
    Wu, Caimei
    Xie, Dihao
    Luo, Meixue
    Yao, Dingyi
    Chen, Min
    Lu, Danyi
    XENOBIOTICA, 2023, 53 (03) : 215 - 222
  • [34] Rev-erbα in the brain is essential for circadian food entrainment
    Delezie, Julien
    Dumont, Stephanie
    Sandu, Cristina
    Reibel, Sophie
    Pevet, Paul
    Challet, Etienne
    SCIENTIFIC REPORTS, 2016, 6
  • [35] Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
    Zhang, Yuxiang
    Fang, Bin
    Emmett, Matthew J.
    Damle, Manashree
    Sun, Zheng
    Feng, Dan
    Armour, Sean M.
    Remsberg, Jarrett R.
    Jager, Jennifer
    Soccio, Raymond E.
    Steger, David J.
    Lazar, Mitchell A.
    SCIENCE, 2015, 348 (6242) : 1488 - 1492
  • [36] Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB
    Meghan H. Murray
    Aurore Cecile Valfort
    Thomas Koelblen
    Céline Ronin
    Fabrice Ciesielski
    Arindam Chatterjee
    Giri Babu Veerakanellore
    Bahaa Elgendy
    John K. Walker
    Lamees Hegazy
    Thomas P. Burris
    Nature Communications, 13
  • [37] How the circadian nuclear orphan receptor REV-ERBα represses transcription: Temporal and spatial phase separation combined
    Schibler, Ueli
    MOLECULAR CELL, 2023, 83 (19) : 3399 - 3401
  • [38] The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
    Gibbs, Julie E.
    Blaikley, John
    Beesley, Stephen
    Matthews, Laura
    Simpson, Karen D.
    Boyce, Susan H.
    Farrow, Stuart N.
    Else, Kathryn J.
    Singh, Dave
    Ray, David W.
    Loudon, Andrew S. I.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (02) : 582 - 587
  • [39] Nuclear hormone receptors for heme:: REV-ERBα and REV-ERBβ are ligand-regulated components of the mammalian clock
    Burris, Thomas P.
    MOLECULAR ENDOCRINOLOGY, 2008, 22 (07) : 1509 - 1520
  • [40] The nuclear receptor REV-ERBα is required for the daily balance of carbohydrate and lipid metabolism
    Delezie, Julien
    Dumont, Stephanie
    Dardente, Hugues
    Oudart, Hugues
    Grechez-Cassiau, Aline
    Klosen, Paul
    Teboul, Michele
    Delaunay, Franck
    Pevet, Paul
    Challet, Etienne
    FASEB JOURNAL, 2012, 26 (08): : 3321 - 3335