Theoretical development and critical analysis of burst frequency equations for passive valves on centrifugal microfluidic platforms

被引：0
作者：
Tzer Hwai Gilbert Thio
Salar Soroori
Fatimah Ibrahim
Wisam Al-Faqheri
Norhayati Soin
Lawrence Kulinsky
Marc Madou
机构：
[1] University of Malaya,Medical Informatics and Biological Micro
[2] University of California,electro
[3] Irvine,mechanical Systems (MIMEMS) Specialized Laboratory, Department of Biomedical Engineering, Faculty of Engineering
[4] University of Malaya,Department of Biomedical Engineering
[5] University of California,Department of Electrical Engineering, Faculty of Engineering
[6] Irvine,Department of Mechanical and Aerospace Engineering
[7] World Class University (WCU),Ulsan National Institute of Science and Technology (UNIST)
来源：
Medical & Biological Engineering & Computing | 2013年 / 51卷
关键词：
Microfluidics; Centrifugal; Compact disc (CD); Burst frequency equation; Passive valve;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This paper presents a theoretical development and critical analysis of the burst frequency equations for capillary valves on a microfluidic compact disc (CD) platform. This analysis includes background on passive capillary valves and the governing models/equations that have been developed to date. The implicit assumptions and limitations of these models are discussed. The fluid meniscus dynamics before bursting is broken up into a multi-stage model and a more accurate version of the burst frequency equation for the capillary valves is proposed. The modified equations are used to evaluate the effects of various CD design parameters such as the hydraulic diameter, the height to width aspect ratio, and the opening wedge angle of the channel on the burst pressure.
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页码：525 / 535
页数：10
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