The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity

被引：0

作者：

George N. Tzanakakis

Andrew N. Margioris

Aristidis M. Tsatsakis

Michael P. Vezeridis

机构：

[1] University of Crete,Department of Clinical Chemistry, School of Medicine

[2] University of Crete,Department of Toxicology, School of Medicine

[3] Brown Medical School,Surgical Service, VA Medical Center

[4] Brown Medical School,Department of Surgery

[5] University of Crete,Department of Histology, School of Medicine

来源：

International Journal of Gastrointestinal Cancer | 2003年 / 34卷 / 1期

关键词：

Pancreatic carcinoma; metastatic potential; cathepsin B; in vitro/in vivo model; ultrastructural characteristics;

D O I：

10.1385/IJGC:34:1:27

中图分类号：

学科分类号：

摘要：

Background. Cathepsin B, a lysosomal cysteine protease, has a major role in the mechanisms of tumor metastasis. The aim of the present work was to examine the correlation between cathepsin B activity and the metastatic potential of human pancreatic cancer.

引用

页码：27 / 38

页数：11