The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity

被引：0
|
作者：
George N. Tzanakakis
Andrew N. Margioris
Aristidis M. Tsatsakis
Michael P. Vezeridis
机构：
[1] University of Crete,Department of Clinical Chemistry, School of Medicine
[2] University of Crete,Department of Toxicology, School of Medicine
[3] Brown Medical School,Surgical Service, VA Medical Center
[4] Brown Medical School,Department of Surgery
[5] University of Crete,Department of Histology, School of Medicine
来源：
International Journal of Gastrointestinal Cancer | 2003年 / 34卷 / 1期
关键词：
Pancreatic carcinoma; metastatic potential; cathepsin B; in vitro/in vivo model; ultrastructural characteristics;
D O I：
10.1385/IJGC:34:1:27
中图分类号：
学科分类号：
摘要：
Background. Cathepsin B, a lysosomal cysteine protease, has a major role in the mechanisms of tumor metastasis. The aim of the present work was to examine the correlation between cathepsin B activity and the metastatic potential of human pancreatic cancer.
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页码：27 / 38
页数：11
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