Barrett’s esophagus

被引：0
作者：
Pech O. [1 ]
May A. [2 ]
机构：
[1] Klinik für Gastroenterologie und interventionelle Endoskopie, Barmherzige Brüder Krankenhaus Regensburg, Prüfeninger Straße 86, Regensburg
[2] Sana Klinikum Offenbach, Offenbach
来源：
Der Gastroenterologe | 2018年 / 13卷 / 4期
关键词：
Adenocarcinoma; Endoscopic gastrointestinal surgery; Gastroesophageal reflux disease; Gastrointestinal endoscopy; Pulsed radiofrequency treatment;
D O I：
10.1007/s11377-018-0268-3
中图分类号：
学科分类号：
摘要：
Barrett’s esophagus is a consequence of chronic gastroesophageal reflux disease and is associated with an increased risk for the development of esophageal adenocarcinoma. Barrett’s esophagus is defined by a columnar-lined distal esophagus with intestinal metaplasia >10 mm and the presence of goblet cells. The increased risk of developing adenocarcinoma follows several steps from low-grade dysplasia over high-grade dysplasia, leading to Barrett’s adenocarcinoma. Early Barrett’s neoplasia can usually be treated endoscopically by means of endoscopic resection followed by an ablative therapy of the remaining non-neoplastic Barrett’s epithelium. In case of more advances adenocarcinoma, surgical resection with or without perioperative chemoradiation or chemotherapy is the treatment of choice. © 2018, Springer Verlag. All rights reserved.
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页码：311 / 321
页数：10
相关论文
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