Pneumonia and Streptococcus pneumoniae vaccine

被引:0
|
作者
Gyu-Lee Kim
Seung-Han Seon
Dong-Kwon Rhee
机构
[1] Sungkyunkwan University,School of Pharmacy
来源
Archives of Pharmacal Research | 2017年 / 40卷
关键词
Pneumonia; Pneumococcal vaccine;
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学科分类号
摘要
Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other microorganisms. Streptococcus pneumoniae, a gram-positive bacterium with over 90 serotypes, is the most common causative agent. Moreover, comorbid factors including heart failure, renal disease, and pulmonary disease could increase the risk of pneumococcal pneumonia. Since the advent of the pneumococcal vaccine in the 1980s, the incidence of pneumonia has decreased significantly. However, current vaccines confer only limited protection against serotypes included in the vaccine. Thus, to overcome this limitation, new types of pneumococcal vaccines have been sought and under clinical trials. In this review, we discuss pneumonia and summarize the various types of pneumococcal vaccines in progress.
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页码:885 / 893
页数:8
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