The effects of NLRP3 inflammasome inhibition by MCC950 on LPS-induced pancreatic adenocarcinoma inflammation

被引:0
作者
Alan Cheuk Keong Yaw
Elaine Wan Ling Chan
Jeremy Kean Yi Yap
Chun Wai Mai
机构
[1] International Medical University,School of Postgraduate Studies
[2] International Medical University,Institute for Research, Development and Innovation
[3] International Medical University,Department of Pharmaceutical Chemistry, School of Pharmacy
来源
Journal of Cancer Research and Clinical Oncology | 2020年 / 146卷
关键词
LPS-induced inflammation; NLRP3 inflammasome; Apoptosis-associated speck-like protein (ASC); NLPR3 inflammasome inhibitor; MCC950; Pancreatic cancer;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2219 / 2229
页数:10
相关论文
共 264 条
[21]  
Dungan LS(2020)Progress in animal models of pancreatic ductal adenocarcinoma J Cancer 11 1555-73
[22]  
Monks BG(2016)Cytokine patterns in cancer patients: a review of the correlation between interleukin 6 and prognosis Oncoimmunology 5 e1093722-831
[23]  
Stutz A(2013)Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma J Invest Dermatol 133 518-885
[24]  
Coll RC(2007)Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation Nat Rev Immunol 7 31-291
[25]  
Hill JR(2013)Causes of death and influencing factors in patients with atrial fibrillation Circulation 128 2192-95
[26]  
Day CJ(2009)The inflammasomes: guardians of the body Annu Rev Immunol 27 229-489
[27]  
Zamoshnikova A(2014)Inflammation and gastrointestinal cancer: an overview Cancer Lett 345 153-564
[28]  
Boucher D(2008)Chronic inflammation and pancreatic cancer Best Pract Res Clin Gastroenterol 22 65-192
[29]  
Massey NL(2018)Role of the NLRP3 inflammasome in cancer Mol Cancer 17 158-62
[30]  
Chitty JL(2008)Role of ASC in hypoxia-mediated cell death in pancreatic cancer Mol Med Rep 1 827-G319