Unusual features of metastatic atypical carcinoid of the larynx

被引：0

作者：

A. Alujević

G. Jurić

R. Šeparović

B. Krušlin

机构：

[1] Department of Pathology,

[2] Firule Clinical Hospital,undefined

[3] Split,undefined

[4] Croatia,undefined

[5] Department of Clinical Pathology,undefined

[6] Rebro Clinical Hospital Center,undefined

[7] Zagreb,undefined

[8] Croatia,undefined

[9] University Hospital for Tumors,undefined

[10] Zagreb,undefined

[11] Croatia,undefined

[12] Department of Clinical Pathology,undefined

[13] Sestre milosrdnice,undefined

[14] Clinical Hospital,undefined

[15] Vinogradska 29,undefined

[16] HR-10000 Zagreb,undefined

[17] Croatia,undefined

来源：

European Archives of Oto-Rhino-Laryngology | 1998年 / 255卷

关键词：

Key words Larynx; Neuroendocrine carcinoma; Carcinoid tumor; Paraganglioma; Metastasis;

D O I：

暂无

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学科分类号：

摘要：

This report describes a case of atypical carcinoid of the larynx with metastatic tumor to cervical lymph nodes showing features similar to paraganglioma. Immunohistochemically, both the primary and metastatic tumor were positive for epithelial membrane antigen, cytokeratin, neuron-specific enolase, chromogranin, synaptophysin, calcitonin and carcinoembryonic antigen. The sustentacular cells in pseudo-cell ball (“Zellballen”) formations were shown by a positive S-100 marker. Electron microscopic analysis revealed numerous neuroendocrine granules measuring 150–250 nm in diameter. Clinical features, histological appearance, histochemical, immunohistochemical and ultrastructural findings, as well as differential diagnosis are discussed.

引用

页码：318 / 321

页数：3