Formosins A–F: Diterpenoids with Anti-microbial Activities from Excoecaria formosana

被引：9

作者：

Lin B.-D. ^{[1
]}

Zhou B. ^{[1
]}

Dong L. ^{[1
]}

Wu Y. ^{[1
]}

Yue J.-M. ^{[1
]}

机构：

[1] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai

来源：

Natural Products and Bioprospecting | 2016年 / 6卷 / 1期

关键词：

Anti-microbial; Clerodane-type; Diterpenoid; Excoecaria formosana; Halimane-type;

D O I：

10.1007/s13659-016-0086-6

中图分类号：

学科分类号：

摘要：

Abstract: Three new halimane-type diterpenoids formosins A–C (1–3), and three clerodane-type diterpenoids formosins D–F (4–6), were isolated from the twigs of Excoecaria formosana. Their structures were assigned on the basis of spectroscopic data analysis. Compounds 1 and 4 showed moderate anti-microbial activities against Bacillus subtilis (MIC = 50 and 50 μg/mL, respectively). Compound 6 exhibited moderate anti-microbial activities against two strains of Helicobacter pylori (Hp-SS1 and ATCC 43504) with MIC values of 50 and 50 μg/mL, respectively. Graphical abstract: [Figure not available: see fulltext.]. © 2016, The Author(s).

引用

页码：57 / 61

页数：4

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