Extracellular vesicles derived from bone marrow mesenchymal stem cells loaded on magnetic nanoparticles delay the progression of diabetic osteoporosis via delivery of miR-150-5p

被引:0
|
作者
Chen Xu
Zhaodong Wang
Yajun Liu
Bangguo Wei
Xiangyu Liu
Keyou Duan
Pinghui Zhou
Zhao Xie
Min Wu
Jianzhong Guan
机构
[1] the First Affiliated Hospital of Bengbu Medical College,Department of Orthopedics
[2] Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College),undefined
[3] Jinan University,undefined
[4] Third Military Medical University of Chinese PLA,undefined
来源
关键词
Diabetic osteoporosis; Bone marrow mesenchymal stem cells; Magnetic nanoparticles; Extracellular vesicles; MicroRNA-150-5p; MMP14; Wnt/β-catenin pathway; Osteogenesis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1257 / 1274
页数:17
相关论文
共 50 条
  • [1] Extracellular vesicles derived from bone marrow mesenchymal stem cells loaded on magnetic nanoparticles delay the progression of diabetic osteoporosis via delivery of miR-150-5p
    Xu, Chen
    Wang, Zhaodong
    Liu, Yajun
    Wei, Bangguo
    Liu, Xiangyu
    Duan, Keyou
    Zhou, Pinghui
    Xie, Zhao
    Wu, Min
    Guan, Jianzhong
    CELL BIOLOGY AND TOXICOLOGY, 2023, 39 (04) : 1257 - 1274
  • [2] Delivery of miR-15b-5p via magnetic nanoparticle-enhanced bone marrow mesenchymal stem cell-derived extracellular vesicles mitigates diabetic osteoporosis by targeting GFAP
    Xu, Chen
    Wang, Zhaodong
    Liu, Yajun
    Duan, Keyou
    Guan, Jianzhong
    CELL BIOLOGY AND TOXICOLOGY, 2024, 40 (01)
  • [3] LncRNA MIAT can regulate the proliferation, apoptosis, and osteogenic differentiation of bone marrow-derived mesenchymal stem cells by targeting miR-150-5p
    Wang, Fei
    Deng, Huimin
    Chen, Jimin
    Wang, Zhaobin
    Yin, Ruofeng
    BIOENGINEERED, 2022, 13 (03) : 6343 - 6352
  • [4] Extracellular vesicles-derived miR-150-5p secreted by adipose-derived mesenchymal stem cells inhibits CXCL1 expression to attenuate hepatic fibrosis
    Du, Zhiyong
    Wu, Tianchong
    Liu, Linsen
    Luo, Biwei
    Wei, Cuifeng
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2021, 25 (02) : 701 - 715
  • [5] Extracellular vesicles derived from bone marrow mesenchymal stem cells ameliorate chronic liver damage via microRNA-136-5p
    Jiang, Xiaodan
    Liu, Zhejun
    You, Hongjie
    Tang, Zuoqing
    Ma, Yun
    Nie, Ruifang
    Yang, Zheng
    Che, Niancong
    Liu, Wenlan
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2024, 480 (2) : 951 - 969
  • [6] Imaging of extracellular vesicles derived from human bone marrow mesenchymal stem cells using fluorescent and magnetic labels
    Dabrowska, Sylwia
    Del Fattore, Andrea
    Karnas, Elzbieta
    Frontczak-Baniewicz, Malgorzata
    Kozlowska, Hanna
    Muraca, Maurizio
    Janowski, Miroslaw
    Lukomska, Barbara
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018, 13 : 1653 - 1664
  • [7] mir-150-5p inhibits the osteogenic differentiation of bone marrow-derived mesenchymal stem cells by targeting irisin to regulate the p38/MAPK signaling pathway
    Qi, Jia-long
    Zhang, Zhi-dong
    Dong, Zhou
    Shan, Tao
    Yin, Zong-sheng
    JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, 2024, 19 (01)
  • [8] mir-150-5p inhibits the osteogenic differentiation of bone marrow-derived mesenchymal stem cells by targeting irisin to regulate the p38/MAPK signaling pathway
    Jia-long Qi
    Zhi-dong Zhang
    Zhou Dong
    Tao Shan
    Zong-sheng Yin
    Journal of Orthopaedic Surgery and Research, 19
  • [9] Extracellular vesicles derived from T-cell acute lymphoblastic leukemia inhibit osteogenic differentiation of bone marrow mesenchymal stem cells via miR-34a-5p
    Yuan, Tian
    Shi, Ce
    Xu, Wen
    Yang, Hong-Liang
    Xia, Bing
    Tian, Chen
    ENDOCRINE JOURNAL, 2021, 68 (10) : 1197 - 1208
  • [10] Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote liver regeneration via miR-20a-5p/PTEN
    Zhang, Jing
    Gao, Juan
    Li, Xianlong
    Lin, Dengna
    Li, Zhihui
    Wang, Jialei
    Chen, Junfeng
    Gao, Zhiliang
    Lin, Bingliang
    FRONTIERS IN PHARMACOLOGY, 2023, 14