Dietary fiber and cardiovascular disease: Experimental and epidemiologic advances

被引:29
作者
Pereira M.A. [1 ]
Pins J.J. [2 ]
机构
[1] Department of Pediatrics, Harvard Medical School, Children’s Hospital, Division of Endocrinology, Boston, MA, 02115, 333 Longwood Avenue
[2] Department of Family Practice and Community Health, University of Minnesota School of Medicine, Minneapolis, MN, 55414, 825 Washington Ave. SE
关键词
Dietary Fiber; Nurse Health Study; Soluble Fiber; Psyllium; Dietary Fiber Intake;
D O I
10.1007/s11883-000-0049-5
中图分类号
学科分类号
摘要
Recently reported experimental studies offer insight into the various mechanisms through which dietary fiber may reduce the risk of cardiovascular disease (CVD) in humans. Although most work has focused on traditional risk factors, studies have begun to explore less studied areas of risk such as fibrinolysis. Epidemiologic results have consistently demonstrated inverse associations between dietary fiber, particularly cereal fiber and whole grain foods, and the development of CVD morbidity and mortality. These associations have been observed in both men and women and are not accounted for by potential confounders such as other dietary and lifestyle factors; nor can they be fully explained by body habitus, antioxidants, and other nutrients found in fiber-rich foods. The evidence to date supports clear recommendations for a diet based on fiber-rich foods.
引用
收藏
页码:494 / 502
页数:8
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[1]  
Glore SR, Treeck DV, Knehaus AW, Guild M, Soluble fiber and serum lipids: a literature review, J Am Diet Assoc, 94, pp. 425-436, (1994)
[2]  
Anderson JW, Hanna TJ, Impact of nondigestible carbohydrates on serum lipoproteins and risk for cardiovascular disease, J Nutr, 129, pp. 1457S-1466S, (1999)
[3]  
Anderson JW, Dietary fiber and human health, Hortic Sci, 25, pp. 1488-1495, (1990)
[4]  
Anderson JW, Allgood LS, Lawrence A, Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials, Am J Clin Nutr, 71, pp. 472-479, (2000)
[5]  
Knopp RH, Superko HR, Davidson M, Long-term blood cholesterol-lowering effects of a dietary fiber supplement, Am J Prev Med, 17, pp. 18-23, (1999)
[6]  
Tai ES, Fok ACK, Chu R, Tan CE, A study to assess the effect of dietary supplementation with soluble fibre (Minolest®) on lipid levels in normal subjects with hypercholesterolaemia, Ann Acad Med Singapore, 28, pp. 209-213, (1999)
[7]  
Jenkins DJA, Kendall CWC, Mehling CC, Combined effect of vegetable protein (soy) and soluble fiber added to a standard cholesterol-lowering diet, Metabolism, 48, pp. 809-816, (1999)
[8]  
Leinonen KS, Poutanen KS, Mykkanen HM, Rye bread decreases serum total and LDL cholesterol in men with moderately elevated serum cholesterol, J Nutr, 130, pp. 164-170, (2000)
[9]  
Davidson MH, Maki KC, Effects of dietary inulin on serum lipids, J Nutr, 129, pp. 1474S-1477S, (1999)
[10]  
Davidson MH, Dugan LD, Stocki J, A low-viscosity soluble-fiber fruit juice supplement fails to lower cholesterol in hypercholesterolemic men and women, J Nutr, 128, pp. 1927-1932, (1998)