Association of hip fracture incidence and intake of calcium, magnesium, vitamin D, and vitamin K

被引:0
作者
Yumi Yaegashi
Toshiyuki Onoda
Kozo Tanno
Toru Kuribayashi
Kiyomi Sakata
Hajime Orimo
机构
[1] School of Medicine,Department of Hygiene and Preventive Medicine
[2] Iwate Medical University,Department of Health and Physical Education, Faculty of Education
[3] Iwate University,undefined
[4] Health Science University,undefined
来源
European Journal of Epidemiology | 2008年 / 23卷
关键词
Ecological study; Hip fracture; Nationwide survey; Nutrients; Regional difference; Vitamin K;
D O I
暂无
中图分类号
学科分类号
摘要
Objective To analyze the association between hip fracture incidence in 12 regional blocks within Japan and dietary intake of four key nutrients: calcium, magnesium, vitamin D, and vitamin K. Design An ecological study. Methods Using data from the 2002 national survey on the incidence of hip fracture and the National Nutritional Survey of Japan, a standardized incidence ratio of hip fracture was calculated, and the association between the standardized incidence ratio and each nutritional intake was assessed for each region using Pearson’s correlation coefficient and partial correlation analysis. Results There were significant correlations between the standardized incidence ratio by region and magnesium, vitamin D, and vitamin K in both men and women, and calcium in women. The strongest inverse correlations were found in vitamin K in both men and women (r = −0.844, P = 0.001, and r = −0.834, P = 0.001, respectively). After adjusting for calcium, magnesium, and vitamin D, the partial correlation between the standardized incidence ratio by regional block and vitamin K was strongest in both men and women (partial correlation coefficient, pcc = −0.673, P = 0.04; pcc = −0.575, P = 0.106, respectively). Conclusions The significant correlation between hip fracture incidence and vitamin K intake, and also regional variations in food patterns, suggest that increasing intake of vegetables and legumes might lead to a decrease in hip fracture incidence in the future. Further, this study suggests that a review of the dietary reference value of vitamin K from the perspective of osteoporosis would be useful.
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页码:219 / 225
页数:6
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