Menopausal symptoms and associated risk factors among postmenopausal women screened for the metabolic syndrome

被引：68

作者：

Chedraui P. ^{[1
,2
]}

Hidalgo L. ^{[1
,2
]}

Chavez D. ^{[1
]}

Morocho N. ^{[1
,2
]}

Alvarado M. ^{[1
]}

Huc A. ^{[1
]}

机构：

[1] Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Institute of Biomedicine, Guayaquil

[2] Foundation for Health and Well Being in the Climacteric FUCLIM, Guayaquil

来源：

Archives of Gynecology and Obstetrics | 2007年 / 275卷 / 3期

关键词：

Health assessment; Latin America; Menopausal symptoms; Metabolic syndrome; Quality of life;

D O I：

10.1007/s00404-006-0239-7

中图分类号：

学科分类号：

摘要：

Background: Although the frequency of menopausal symptoms may vary according to the studied population, in general severe intensity has been related to lower quality of life. Objective: To assess the frequency of menopausal symptoms and involved risk factors in an Ecuadorian postmenopausal population. Methods: Postmenopausal women that participated in a metabolic syndrome screening program were interviewed with the Menopause-specific quality of life questionnaire (MENQOL) in order to determine the most frequently presenting menopausal symptoms and correlate these symptoms with socio-demographic data and the main results of the screening program. Results: Three hundred and twenty-five postmenopausal women (n = 325) were surveyed with the MENQOL. Mean age of participants was 55.9 ± 8.1 years (median: 54 years). The most frequently presenting symptoms were: hot flushes (53.3%), sweating (49.2%), poor memory (80.6%), feeling depressed (67.4%), aching in muscles and joints (84%), drying of their skin (85.5%), avoiding intimacy (76.2%) and change in their sexual desire (76.5%). Multivariate analysis determined that abdominal obesity was a significant risk factor for presenting hot flushes, depression and muscle and joint pain. High triglyceride levels were associated to higher rates of sweating and depression. While women with basal hyperglycemia were associated to dry skin and changes in sexual desire in a higher proportion, those who were older and with more years of menopause onset were related less frequently to vasomotor symptoms. Older age was also significantly associated in a higher rate to dry skin. Conclusion: In this postmenopausal Ecuadorian population, the frequency of menopausal symptoms, as assessed with the MENQOL, was found to be relatively similar to other Latin and non-Latin American populations and associated to age, hormonal status and related metabolic conditions. © 2006 Springer-Verlag.

引用

页码：161 / 168

页数：7

共 33 条

[1]

Blumel J.E., Brandt A., Tacla X., Symptomatic profile of the climacteric female clinical experience, Rev Med Chil, 120, pp. 1017-1021, (1992)

[2]

Blumel J.E., Castelo-Branco C., Binfa L., Gramegna G., Tacla X., Aracena B., Cumsille M.A., Sanjuan A., Quality of life after the menopause: A population study, Maturitas, 34, pp. 17-23, (2000)

[3]

Blumel J.E., Castelo-Branco C., Roncagliolo M.E., Binfa L., Sarra S., Cardiovascular risk factors in a cohort of middleaged women, Rev Med Chil, 131, pp. 381-389, (2003)

[4]

Blumel J.E., Chedraui P., Calle A., Et al., Age of menopause presentation in Latin America. Menopause, 13, pp. 706-712, (2006)

[5]

Buckler H., The menopause transition: Endocrine changes and clinical symptoms, J Br Menopause Soc, 11, pp. 61-65, (2005)

[6]

Burger H.G., Dudley E.C., Robertson D.M., Dennerstein L., Hormonal changes in the menopause transition, Recent Prog Horm Res, 57, pp. 257-275, (2002)

[7]

Carr M.C., The emergence of the metabolic syndrome with menopause, J Clin Endocrinol Metab, 88, pp. 2404-2411, (2003)

[8]

Castelo-Branco C., Blumel J.E., Araya H., Riquelme R., Castro G., Haya J., Et al., Prevalence of sexual dysfunction in a cohort of middle-aged women: Influences of menopause and hormone replacement therapy, J Obstet Gynaecol, 23, pp. 426-430, (2003)

[9]

Castelo-Branco C., Blumel J.E., Roncagliolo M.E., Haya J., Bolf D., Binfa L., Tacla X., Colondron M., Age, menopause and hormone replacement therapy influences on cardiovascular risk factors in a cohort of middle-aged Chilean women, Maturitas, 45, pp. 205-212, (2003)

[10]

Chedraui P., Hidalgo L., Morocho N., Alvarado M., Chavez D., Huc A., Metabolic syndrome in postmenopausal Ecuadorian women, Climacteric, 8, (2005)

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