Anti-oxidant activities of fucosterol from the marine algaePelvetia siliquosa

被引：0

作者：

Sanghyun Lee

Yeon Sil Lee

Sang Hoon Jung

Sam Sik Kang

Kuk Hyun Shin

机构：

[1] Seoul National University,Natural Products Research Institute

[2] World Sea Green Co. Ltd.,Seokwon Life Science Research Institute

来源：

Archives of Pharmacal Research | 2003年 / 26卷

关键词：

Fucaceae; Fucosterol; Anti-oxidant enzymes; s-Transaminases CCI; -intoxication;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The anti-oxidant activities of fucosterol isolated from the marine algaePelvetia siliquosa were investigated. Fucosterol exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCI4-intoxication in rats. Fucosterol inhibited the sGOT and sGPT activities by 25.57 and 63.16%, respectively. Fucosterol showed the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-px) activities by 33.89, 21.56 and 39.24%, respectively, in CCI4-intoxicated rats. These results suggest that fucosterol possess not only the anti-oxidant, but also the hepatoprotective activities in rats.

引用

页码：719 / 722

页数：3

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