Serum exosomal hsa-circ-0004771 modulates the resistance of colorectal cancer to 5-fluorouracil via regulating miR-653/ZEB2 signaling pathway

被引:0
|
作者
Xiao-Xue Qiao
Hui-Bo Shi
Li Xiao
机构
[1] Fujian Medical University,The Third Clinical Medical College (School of Clinical Medicine)
[2] Zhongshan Hospital Affiliated to Xiamen University,Department of Oncology
[3] Huazhong University of Science and Technology,Department of Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College
[4] Huazhong University of Science and Technology,Department of Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Hospital, Tongji Medical College
[5] Huazhong University of Science and Technology,Department of NHC Key Laboratory of Organ Transplantation, Tongji Hospital, Tongji Medical College
[6] Huazhong University of Science and Technology,Department of Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Tongji Medical College
来源
Cancer Cell International | / 23卷
关键词
Colorectal cancer; 5-fluorouracil; Drug-resistance; Serum exosome; Hsa-circ-0004771/miR-653/ZEB2 axis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 10 条
  • [1] Serum exosomal hsa-circ-0004771 modulates the resistance of colorectal cancer to 5-fluorouracil via regulating miR-653/ZEB2 signaling pathway
    Qiao, Xiao-Xue
    Shi, Hui-Bo
    Xiao, Li
    CANCER CELL INTERNATIONAL, 2023, 23 (01)
  • [2] Circular RNA hsa_circ_ 0004650 Enhances 5-Fluorouracil Resistance in Gastric Cancer via Sponging miR-145-5p
    Zhou, Fusheng
    Zhuo, Jialong
    Xu, Xudong
    Pan, Duyi
    Cai, Chenwen
    Huang, Jiaxin
    Zhao, Xianguang
    Mao, Qiqi
    Jiang, Xiaoyun
    Sun, Xu
    Zhong, Liang
    Gao, Nan
    Chen, Jiajie
    ANTICANCER RESEARCH, 2025, 45 (01) : 173 - 187
  • [3] NEK2 promotes cancer cell progression and 5-fluorouracil resistance via the Wnt/β-catenin signaling pathway in colorectal cancer
    Cui, Facai
    Chen, Yu
    Wu, Xiaoyu
    Zhao, Weifeng
    DISCOVER ONCOLOGY, 2025, 16 (01)
  • [4] Syndecan-2, negatively regulated by miR-20b-5p, contributes to 5-fluorouracil resistance of colorectal cancer cells via the JNK/ERK signaling pathway
    Hua, Ruheng
    Zhang, Yan
    Yan, Xiyue
    Tang, Dong
    Li, Xiaolong
    Ni, Qingfeng
    Wang, Daorong
    Zhu, Jianwei
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 53 (11) : 1547 - 1557
  • [5] Exosome-Mediated Transfer of circ_0000338 Enhances 5-Fluorouracil Resistance in Colorectal Cancer through Regulating MicroRNA 217 (miR-217) and miR-485-3p
    Zhao, Kui
    Cheng, Xiaohui
    Ye, Zhenyu
    Li, Yecheng
    Peng, Wei
    Wu, Yongyou
    Xing, Chungen
    MOLECULAR AND CELLULAR BIOLOGY, 2021, 41 (05)
  • [6] 23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling
    Fan, Zeping
    Cui, Yaru
    Chen, Lanying
    Liu, Peng
    Duan, Wenbin
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2024, 73 (05)
  • [7] 23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling
    Zeping Fan
    Yaru Cui
    Lanying Chen
    Peng Liu
    Wenbin Duan
    Cancer Immunology, Immunotherapy, 73
  • [8] FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway
    Liu, Chao
    Zhao, Yan
    Wang, Jianing
    Yang, Yan
    Zhang, Yan
    Qu, Xinliang
    Peng, Sishi
    Yao, Zhaoying
    Zhao, Shuli
    He, Bangshun
    Mi, Qiongyu
    Zhu, Yubing
    Liu, Xiuting
    Zou, Jianjun
    Zhang, Xu
    Du, Qianming
    CANCER LETTERS, 2020, 470 : 29 - 42
  • [9] MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil
    Shi, Liang
    Wu, Lili
    Chen, Zhanguo
    Yang, Jianrong
    Chen, Xiaofei
    Yu, Fangyou
    Zheng, Fang
    Lin, Xiangyang
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2015, 35 (06) : 2333 - 2348
  • [10] Circular RNA sterile alpha motif domain containing 4A contributes to cell 5-fluorouracil resistance in colorectal cancer by regulating the miR-545-3p/6-phosphofructo-2-kinase/fructose-2,6-bisphosphataseisotype 3 axis
    Gao, Yang
    Liu, Chen
    Xu, Xiaoyun
    Wang, Yijing
    Jiang, Yuanyuan
    ANTI-CANCER DRUGS, 2022, 33 (06) : 553 - 563