An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening

被引:0
作者
Biao Wang
Bang-Shun He
Xiao-Lan Ruan
Jiang Zhu
Rui Hu
Jie Wang
Ying Li
Yun-Huang Yang
Mai-Li Liu
机构
[1] Chinese Academy of Sciences,Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics
[2] Nanjing First Hospital,Wuhan National Laboratory for Optoelectronics
[3] Nanjing Medical University,Department of Laboratory Medicine
[4] Renmin Hospital,Department of Hematology
[5] Wuhan University,Canary Center at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine
[6] University of Chinese Academy of Sciences,undefined
[7] Stanford University,undefined
来源
Military Medical Research | / 9卷
关键词
Microfluidics; Single-cell analysis; Leukemia; High-throughput drug screening; Single-cell cloning;
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[1]  
Soverini S(2011)BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet Blood 118 1208-1215
[2]  
Hochhaus A(2020)Effect of dasatinib vs imatinib in the treatment of pediatric philadelphia chromosome–positive acute lymphoblastic leukemia: a randomized clinical trial JAMA Oncol 6 358-366
[3]  
Nicolini FE(2019)Single cell sequencing reveals evolution of tumor heterogeneity of acute myeloid leukemia on quizartinib Blood 134 1440-1137
[4]  
Gruber F(2016)Translating leukemia stem cells into the clinical setting: harmonizing the heterogeneity Exp Hematol 44 1130-14772
[5]  
Lange T(2019)Current approaches in identification and isolation of cancer stem cells J Cell Physiol 234 14759-168
[6]  
Saglio G(2017)Single-cell multiomics: multiple measurements from single cells Trends Genet 33 155-781
[7]  
Shen S(2021)Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses Sci Adv 7 eabf9840-1251
[8]  
Chen X(2019)Recent advances in single cell manipulation and biochemical analysis on microfluidics Analyst 144 766-11907
[9]  
Cai J(2021)Recent advances in microfluidic platforms for programming cell-based living materials Adv Mater 33 1238-9665
[10]  
Yu J(2017)Microfluidics cell loading-dock system: Ordered cellular array for dynamic lymphocyte-communication study Adv Biosyst 1 11899-12