Oral premalignancy: New methods of detection and treatment

被引：44
作者：
Gillenwater A. [1 ]
Papadimitrakopoulou V. [1 ]
Richards-Kortum R. [1 ]
机构：
[1] Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030
来源：
Current Oncology Reports | 2006年 / 8卷 / 2期
关键词：
Epidermal Growth Factor Receptor; Optical Coherence Tomography; Oral Cancer; Oral Squamous Cell Carcinoma; Oral Leukoplakia;
D O I：
10.1007/s11912-006-0050-4
中图分类号：
学科分类号：
摘要：
Oral carcinogenesis proceeds through a stepwise accumulation of genetic damage over time. Because the oral cavity is easy to examine and risk factor for oral cancer are known, there is great opportunity to improve patient outcomes through diagnosis and treatment of premalignant lesions before the development of invasive oral carcinoma. This review provides a summary of developments in detection and diagnosis of oral premalignant lesions and innovative approaches to management of early oral neoplasia. These technological and therapeutic advances are much needed to improve the poor outcomes associated with oral cancer due to our inability to diagnose and treat this disease at an early, curable stage. © 2006 by Current Science Inc.
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页码：146 / 154
页数：8
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