Interferon free hepatitis C treatment regimens: The beginning of another era

被引:7
作者
Fred Poordad
Grace M. Chee
机构
[1] Hepatology and Liver Transplantation, Cedars-Sinai Medical Center, Los Angeles, CA 90048
[2] Hepatology Department, Cedars-Sinai Medical Center, Los Angeles, CA 90048
关键词
Direct acting antivirals; Hepatitis C; Interferon; Interferon free; Polymerase inhibitor; Protease inhibitor; Ribavirin; SVR;
D O I
10.1007/s11894-011-0229-1
中图分类号
学科分类号
摘要
Hepatitis C is a virus affecting millions worldwide and is a major health risk. With the potentially severe adverse event profile of the current backbone of therapy, interferon, there is an impetus to discover interferon free treatment regimens. With the development of new oral direct acting antivirals, interferon free regimens may be available in the next few years. This article discusses some of the preliminary data from interferon free studies. © 2011 Springer Science+Business Media, LLC.
引用
收藏
页码:74 / 77
页数:3
相关论文
共 50 条
  • [41] Interferon-free therapies for chronic hepatitis C: toward a hepatitis C virus-free world?
    Gentile, Ivan
    Buonomo, Antonio Riccardo
    Zappulo, Emanuela
    Borgia, Guglielmo
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2014, 12 (07) : 763 - 773
  • [42] Future hepatitis C virus treatment: interferon-sparing combinations
    Gane, Edward
    LIVER INTERNATIONAL, 2011, 31 : 62 - 67
  • [43] Combination therapy with interferon and ribavirin in the treatment of chronic hepatitis C infection
    Battaglia, AM
    Hagmeyer, KO
    ANNALS OF PHARMACOTHERAPY, 2000, 34 (04) : 487 - 494
  • [44] Uric acid nephrolithiasis associated with interferon and ribavirin treatment of hepatitis C
    Fontana, RJ
    DIGESTIVE DISEASES AND SCIENCES, 2001, 46 (04) : 920 - 924
  • [45] Superiority of Interferon-Free Regimens for Chronic Hepatitis C The Effect on Health-Related Quality of Life and Work Productivity
    Younossi, Zobair M.
    Stepanova, Maria
    Esteban, Rafael
    Jacobson, Ira
    Zeuzem, Stefan
    Sulkowski, Mark
    Henry, Linda
    Nader, Fatema
    Cable, Rebecca
    Afendy, Mariam
    Hunt, Sharon
    MEDICINE, 2017, 96 (07)
  • [46] The adverse effects of interferon-free regimens in 149816 chronic hepatitis C treated Egyptian patients
    Attia, D.
    El Saeed, K.
    Elakel, W.
    El Baz, T.
    Omar, A.
    Yosry, A.
    Elsayed, M. H.
    Said, M.
    El Raziky, M.
    Anees, M.
    Doss, W.
    El Shazly, Y.
    Wedemeyer, H.
    Esmat, G.
    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2018, 47 (09) : 1296 - 1305
  • [47] Hepatitis C virus genotype 4-infection and interferon-free treatment in Egypt
    Kanda, Tatsuo
    Matsuoka, Shunichi
    Moriyama, Mitsuhiko
    HEPATOLOGY INTERNATIONAL, 2018, 12 (04) : 291 - 293
  • [48] Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection
    Chayama, Kazuaki
    Mitsui, Fukiko
    Hayes, C. Nelson
    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2015, 9 (01) : 21 - 30
  • [49] Clinical characteristics and antiviral therapy in patients infected with hepatitis C virus in the interferon -free era
    Brzdek, Michal
    Dobrowolska, Krystyna
    Pabjan, Pawel
    Zarebska-Michaluk, Dorota
    POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ, 2022, 132 (09):
  • [50] Albumin-interferon-α in the treatment of chronic hepatitis C
    Balan, Vijayan
    FUTURE VIROLOGY, 2006, 1 (03) : 269 - 278