Health-Related Quality of Life Scores Underestimate the Impact of Major Complications in Lumbar Degenerative Scoliosis Surgery

被引：1

作者：

Glassman S.D. ^{[1
]}

Bridwell K.H. ^{[2
]}

Shaffrey C.I. ^{[3
]}

Edwards C.C., II ^{[4
]}

Lurie J.D. ^{[5
]}

Baldus C.R. ^{[2
]}

Carreon L.Y. ^{[1
]}

机构：

[1] Norton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, 40202, KY

[2] Department of Orthopaedic Surgery, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8233, St. Louis, 63110, MO

[3] Department of Neurosurgery, University of Virginia, PO Box 800212, Charlottesville, 22908, VA

[4] The Maryland Spine Center at Mercy Medical Center, 301 St. Paul Place, Baltimore, 21202, MD

[5] Department of Medicine, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, 03756, NH

来源：

Spine Deformity | 2018年 / 6卷 / 1期

关键词：

Adult spinal deformity; Complications; Lumbar scoliosis; Patient-reported outcomes; Prospective cohort;

D O I：

10.1016/j.jspd.2017.05.003

中图分类号：

学科分类号：

摘要：

Study Design Retrospective cohort. Objective To examine Charlson Comorbidity Index (CCMI) as a marker for deterioration in health status not reflected in standard Health Related Quality of Life (HRQOL) measures. Summary of Background Data HRQOL has become a primary metric for assessing outcomes following spinal deformity surgery. However, studies have reported limited impact of complications on postoperative HRQOL outcomes. Methods We examined serial CCMI, complications, and HRQOL outcomes for 138 adult lumbar deformity patients treated surgically with a minimum two-year follow-up that included 126 females (91%) with a mean age of 59.8 years (range, 40.2–78.5). Patients with no, minor, or major complications were compared at baseline and at one and two years postoperation. Results Minor complications were observed in 26 patients (19%) and major complications in 15 (11%). Major complications included motor deficit (7), deep vein thrombosis (4), and respiratory failure (3). There was no difference in preoperative SF-36 Physical Component Summary or Scoliosis Research Society–22R (SRS-22R) scores among the groups at baseline. Preoperative CCMI was lowest in the No Complication group (3.52 ± 1.70) followed by the Major (4.00 ± 1.13) and Minor Complication groups (4.15 ± 1.71, p =.165). At one year, there was a significantly greater CCMI deterioration in the Major Complication group (0.80 ± 1.01) compared to both the Minor (0.08 ± 0.27) and No Complication groups (0.27 ± 0.47, p <.001). There was no significant difference in SF-36 Physical Component Summary or SRS-22R scores among the three groups. Similar findings were observed at two years. Conclusions Despite similar one- and two-year HRQOL improvement, patients with major complications had greater deterioration in CCMI. As CCMI is predictive of medical and surgical risk, patients who sustained a major complication now carry a greater likelihood of adverse outcomes with future interventions, including any subsequent spinal surgery. Although this increased risk may not alter the patient's perception of his or her current health status, it may be important, and should be recognized as part of the shared decision-making process. Level of Evidence Level II, high-quality prognostic study. © 2017 Scoliosis Research Society

引用

页码：67 / 71

页数：4

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