Soluble guanylate cyclase and cGMP-dependent protein kinase I expression in the human corpus cavernosum

被引：0

作者：

T Klotz

W Bloch

J Zimmermann

P Ruth

U Engelmann

K Addicks

机构：

[1] University of Cologne,Department of Urology

[2] Institute I of Anatomy,undefined

[3] University of Cologne,undefined

[4] Institute of Pharmacology,undefined

[5] TU University of Munich,undefined

来源：

International Journal of Impotence Research | 2000年 / 12卷

关键词：

corpus cavernosum; cGMP-dependent kinase I; impotence; soluble guanylate cyclase;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Nitric oxide (NO) as a mediator in smooth muscle cells causes rapid and robust increases in cGMP levels. The cGMP-dependent protein kinase I has emerged as an important signal transduction mediator for smooth muscle relaxation. The purpose of this study was to examine the existence and distribution of two key enzymes of the NO/cGMP pathway, the cGMP-dependent kinase I (cGK I) and the soluble guanylate cyclase (sGC) in human cavernosal tissue.

引用

页码：157 / 164

页数：7