Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats

被引:0
作者
Lunyin Yu
Charles A Hales
机构
[1] Massachusetts General Hospital,Pulmonary and Critical Care Unit, Department of Medicine
[2] Harvard Medical School,undefined
来源
Respiratory Research | / 12卷
关键词
Pulmonary Hypertension; Bone Marrow Cell; Vascular Remodel; CXCR4 Expression; Pulmonary Artery Smooth Muscle Cell;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 261 条
[1]  
Stenmark R(2006)Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms Circ Res 99 675-691
[2]  
Fagan K(2001)Pulmonary vascular remodeling: a target for therapeutic intervention in pulmonary hypertension Pharmacol Ther 92 1-20
[3]  
Frid MG(2003)The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases Am J Respir Crit Care Med 167 1676-86
[4]  
Jeffery TK(2002)Structure, function, and inhibition of chemokines Annu Rev Pharmacol Toxicol 42 469-99
[5]  
Wanstall JC(2004)Chemokines Dev Comp Immunol 28 443-60
[6]  
Phillips RJ(2006)CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment Blood 107 1761-7
[7]  
Burdick MD(2007)Chemokines in vascular remodeling Thromb Haemost 97 730-7
[8]  
Lutz M(2007)The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis Trends Immunol 28 299-307
[9]  
Belperio JA(2008)Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha Circ Res 102 1036-45
[10]  
Keane MP(2008)A small molecule CXCR4 antagonist inhibits neointima formation and smooth muscle progenitor cell mobilization after arterial injury J Thromb Haemost 6 1812-5