The evident and the hidden factors of vitamin D status in older people during COVID-19 pandemic

被引：3

作者：

Schmidt Azevedo P. ^{[1
]}

Fock R.A. ^{[2
]}

Pereira F.L. ^{[1
]}

dos Santos P.P. ^{[1
]}

Ferro F.C. ^{[1
]}

Sacco N. ^{[1
]}

Polegato B.F. ^{[1
]}

Zornoff L.M. ^{[1
]}

Okoshi M.P. ^{[1
]}

Achterberg W. ^{[3
]}

de Paiva S.R. ^{[1
]}

机构：

[1] Internal Medicine Department, Botucatu Medical School, São Paulo State University, Av. Prof Mario Rubens Guimarães Montenegro s/n, Botucatu

[2] Experimental Hematology Laboratory, Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo

[3] Department of Public Health and Primary Care, Leiden University Medical Center, Leiden

来源：

Nutrire | / 46卷 / 1期

关键词：

Care homes; COVID-19; Frailty; Older people; Vitamin D;

D O I：

10.1186/s41110-020-00131-3

中图分类号：

学科分类号：

摘要：

Purpose: Considering the COVID-19 pandemic, vitamin D is a target of research and speculation. Lockdown or home isolation reduces sunlight exposition and increases the risk of vitamin D deficiency. Special attention is needed for older people at risk of both severe forms of COVID-19 and vitamin D deficiency. This review aims to highlight the association of vitamin D and COVID-19 in two instances, the direct influence of vitamin D on the immune system, and the indirect risks for other vitamin D deficiency-related diseases, such as musculoskeletal properties in older persons. Methods: We performed a narrative review. Results: Whether vitamin D deficiency is associated with COVID-19 poor prognosis, and if vitamin D supplementation may improve the post-infection outcomes is still unclear. In any case, the pandemic generates indirect burden, such as the sequence: home isolation, low sunlight exposition, vitamin D deficiency, and fragility fractures. Conclusion: Therefore, it is time to debate how to optimize vitamin D status in older people, especially during the COVID-19 pandemic. © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature.

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